NIH-funded research NIH-funded research

Couples-based support to reduce unhealthy drinking and boost PrEP use for HIV prevention

Official title: Couples motivational interviewing and biological feedback to address unhealthy alcohol use and HIV prevention among sexual minority men

Funded at University of California, San Francisco · NIH-11422371 · Data updated 2026-11-12

A coordinated program helps couples where one or both partners are at risk for HIV by addressing heavy drinking and promoting HIV prevention through PrEP.

More Alcohol Use research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco
NIH-funded
Lab location1 site (San Francisco, United States)
Project startSeptember 25, 2025
Project endAugust 31, 2030
Funding year2026
Award (this year)$399,249
NIH project number5P60AA032189-02
Project IDNIH-11422371 on NIH RePORTER

Who could benefit from this research

Could help

Couples where at least one partner is at risk for HIV and is open to reducing alcohol use and considering PrEP.

Less likely to help

Couples not interested in addressing alcohol use or PrEP, or those with contraindications to PrEP.

What this research studies

This project tests a couple-focused approach that blends motivational interviewing with real-time feedback on alcohol use to support shared goals for health. It builds on successful couple-based interventions and adds new biological feedback tools like a mobile breathalyzer and PEth testing to strengthen motivation and accountability. The study aims to see whether these components improve PrEP uptake and adherence within romantic partnerships at risk for HIV. Participants will be recruited through clinics and community settings in the San Francisco area and related networks.

Why it matters

Potential benefit: If successful, the program could reduce risky drinking and increase PrEP use among couples, lowering HIV transmission risk.

How similar studies have gone: Previous work with individuals shows benefit; this study extends the approach to couples to address relationship dynamics.

Where this research is happening

  • University of California, San Francisco
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Conroy, Amy Anne — University of California, San Francisco
  • Study coordinator: Conroy, Amy Anne

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.