COPD in people with HIV: risks, care quality, and outcomes
Official title: Risk factors for chronic obstructive pulmonary disease exacerbations, quality of care, and outcomes in people with HIV
Funded at University of Pittsburgh at Pittsburgh · NIH-11362714 · Data updated 2026-11-12
This effort looks at how chronic lung disease affects people living with HIV and how care quality relates to their outcomes.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $163,188 |
| NIH project number | 5K08HL169023-04 |
| Project ID | NIH-11362714 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults living with HIV who are at risk for or have COPD, including those with recent COPD exacerbations.
✕Less likely to help
Patients without HIV or COPD are unlikely to benefit directly from this grant’s focus.
What this research studies
The project focuses on understanding why people with HIV have higher risk of COPD exacerbations and worse outcomes after these events. It will examine risk factors, how HIV influences recovery after COPD flares, and whether COPD care aligns with guidelines in people with HIV. The study aims to link HIV status, treatment patterns, and clinical outcomes to identify opportunities to improve care. Researchers will analyze patient data to see how age, smoking, and HIV control affect COPD episodes and post-exacerbation results.
Why it matters
Potential benefit: If successful, findings could lead to better prevention and management of COPD for people with HIV, potentially reducing hospitalizations and deaths.
How similar studies have gone: Previous research suggests HIV increases COPD risk, but data on post-exacerbation outcomes and care quality in HIV are limited.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Konstantinidis, Ioannis — University of Pittsburgh at Pittsburgh
- Study coordinator: Konstantinidis, Ioannis
Related research
Other NIH-funded projects on the same topics.
-
Investigating COPD risks and care quality in people living with HIV
This study is looking at how living with HIV affects people who have chronic obstructive pulmonary disease (COPD) and what can be done to improve their care, so if you have both conditions, your experience and treatment could get better!
-
Ethics-aware Multimodal AI for COPD prevention, diagnosis, and treatment
A broad AI model uses diverse health data to help predict and manage COPD in people, with an emphasis on ethics and fairness.
-
Positive airway pressure therapy for older veterans with COPD and sleep apnea overlap
A plan to see if using a CPAP/BAP therapy improves sleep, thinking, and quality of life for older veterans who have both COPD and sleep apnea.
-
Understanding how microbes and our bodies shape HIV-related COPD in LMICs
This project looks at how interactions between the human body and microbes may influence COPD in people living with HIV in low- and middle-income countries.
-
Anti-EMAP II antibody as a first-in-class treatment for COPD-related pulmonary hypertension
A first-in-class antibody treatment is being developed to help people with COPD-related pulmonary hypertension by blocking EMAP II, a molecule involved in lung injury and inflammation.
-
Non-coding RNA and COPD: how RNA structure changes with disease
A COPD research project explores how non-coding RNA structures in adults with COPD change due to genetic differences and how this affects gene activity.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.