Investigating COPD risks and care quality in people living with HIV
Official title: Risk factors for chronic obstructive pulmonary disease exacerbations, quality of care, and outcomes in people with HIV
Funded at University of Pittsburgh at Pittsburgh · NIH-10868729 · Data updated 2026-11-12
This study is looking at how living with HIV affects people who have chronic obstructive pulmonary disease (COPD) and what can be done to improve their care, so if you have both conditions, your experience and treatment could get better!
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $163,068 |
| NIH project number | 5K08HL169023-02 |
| Project ID | NIH-10868729 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults over 21 years old who are living with HIV and have been diagnosed with chronic obstructive pulmonary disease.
✕Less likely to help
Patients who do not have HIV or chronic obstructive pulmonary disease may not receive any benefit from this research.
What this research studies
This research focuses on understanding the risk factors for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in individuals living with HIV. It aims to identify how HIV infection influences the outcomes after AECOPD and examines the quality of COPD care provided to these patients. By comparing people with HIV to those without, the study will explore the relationship between HIV-specific factors, traditional risk factors, and the effectiveness of COPD treatment. The findings could help improve care strategies for individuals affected by both HIV and COPD.
Why it matters
Potential benefit: If successful, this research could lead to better management and treatment strategies for patients with COPD who are also living with HIV.
How similar studies have gone: Previous research has indicated that understanding the interplay between HIV and COPD can lead to improved patient outcomes, suggesting that this approach has potential for success.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Konstantinidis, Ioannis — University of Pittsburgh at Pittsburgh
- Study coordinator: Konstantinidis, Ioannis
Related research
Other NIH-funded projects on the same topics.
-
COPD in people with HIV: risks, care quality, and outcomes
This effort looks at how chronic lung disease affects people living with HIV and how care quality relates to their outcomes.
-
Ethics-aware Multimodal AI for COPD prevention, diagnosis, and treatment
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A plan to see if using a CPAP/BAP therapy improves sleep, thinking, and quality of life for older veterans who have both COPD and sleep apnea.
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Understanding how microbes and our bodies shape HIV-related COPD in LMICs
This project looks at how interactions between the human body and microbes may influence COPD in people living with HIV in low- and middle-income countries.
-
Anti-EMAP II antibody as a first-in-class treatment for COPD-related pulmonary hypertension
A first-in-class antibody treatment is being developed to help people with COPD-related pulmonary hypertension by blocking EMAP II, a molecule involved in lung injury and inflammation.
-
Non-coding RNA and COPD: how RNA structure changes with disease
A COPD research project explores how non-coding RNA structures in adults with COPD change due to genetic differences and how this affects gene activity.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.