NIH-funded research R01 grant

Community pharmacists helping rural Appalachia quit smoking

Official title: Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia

Funded at University of Virginia · NIH-11330162 · Data updated 2026-11-12

A real-world study tests using local pharmacists to deliver a Medicaid-style medication-management approach to help rural smokers in Appalachia quit and stay quit.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Virginia
NIH-funded
Lab location1 site (Charlottesville, United States)
Project startSeptember 8, 2022
Project endMay 31, 2028
Funding year2026
Award (this year)$1,017,423
NIH project number5R01CA267963-04
Project IDNIH-11330162 on NIH RePORTER

Who could benefit from this research

Could help

Adults in rural Appalachia who smoke and are interested in quitting, receiving care through participating community pharmacies.

Less likely to help

Smokers not engaging with pharmacists or those unwilling to use cessation medications may see limited benefit.

What this research studies

This project partners with community pharmacists in rural Appalachia to deliver a structured QuitAid program, aiming to integrate smoking-cessation support into routine primary care visits. Pharmacists use medication therapy management strategies to support adherence to cessation aids and to bill for their counseling time, making the service sustainable in underserved communities. The study uses a pragmatic design to see how well this pharmacist-led approach works in everyday clinic settings and how it can be adopted in similar rural areas. Outcomes include quit rates, adherence to cessation medications, and implementation metrics such as adoption by pharmacies and reimbursement processes.

Why it matters

Potential benefit: If successful, patients in rural Appalachia could access more convenient, pharmacist-led support to quit smoking and reduce cancer risk.

How similar studies have gone: Prior pharmacist-led cessation approaches show promise, but this pragmatic program tests scalable real-world deployment in a high-need region.

Where this research is happening

  • University of Virginia
    Charlottesville, United States
    Active

Researchers

  • Principal investigator: Little, Melissa Ashley — University of Virginia
  • Study coordinator: Little, Melissa Ashley

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.