NIH-funded research R01 grant

Community health worker support to help people with serious mental illness quit smoking

Official title: Evaluation of Community Health Worker Support to Improve Tobacco Use Disorder Outcomes in Medicaid Beneficiaries with Serious Mental Illness

Funded at Massachusetts General Hospital · NIH-11225257 · Data updated 2026-11-12

This project trains Medicaid behavioral health staff to act as community health workers who help adults with serious mental illness stop using tobacco.

More Tobacco Use research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startMay 1, 2026
Project endFebruary 28, 2031
Funding year2026
Award (this year)$740,451
NIH project number1R01DA061887-01A1
Project IDNIH-11225257 on NIH RePORTER

Who could benefit from this research

Could help

Adults with serious mental illness who are enrolled in Medicaid, currently use tobacco, and receive care through the partnering behavioral health sites are the ideal candidates.

Less likely to help

People who are not enrolled in the partnered Medicaid ACO or who are not interested in quitting tobacco are unlikely to benefit from this program.

What this research studies

You would work with a trained community health worker who is part of your Medicaid behavioral health team to get coaching, help accessing stop-smoking medicines, and support for social needs that make quitting harder. The program gives brief training so existing staff can function as CHWs and coordinates with your clinical providers for medications and follow-up. About 937 adults with serious mental illness who smoke will be enrolled through Medicaid behavioral health sites and followed for smoking, heart health, and mental health outcomes. The team will compare how often people use cessation treatments and achieve abstinence when they receive this CHW support versus usual care.

Why it matters

Potential benefit: If successful, this approach could raise quit rates, improve cardiovascular and mental health, and reduce premature deaths among Medicaid patients with serious mental illness.

How similar studies have gone: Prior work showed that trained lay CHWs plus provider education doubled tobacco abstinence in people with serious mental illness, but using existing Medicaid behavioral health staff as CHWs within Medicaid ACOs is a newer approach.

Where this research is happening

  • Massachusetts General Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Evins, a Eden — Massachusetts General Hospital
  • Study coordinator: Evins, a Eden

Related research

Other NIH-funded projects on the same topics.

  • VR-based attentional bias as a biomarker for tobacco use disorder

    A study at UC San Diego is testing a virtual reality task to see if attentional bias can serve as a biomarker to help treat cigarette addiction.

    NIH research University of California, San Diego · La Jolla, United States · NIH-11350932

  • Smoking-cessation meds with a team approach for people with HIV (SMARTTT)

    A multi-site study tests a team-based plan using medication and rewards to help people with HIV quit smoking.

    NIH research Yale University · New Haven, United States · NIH-11169520

  • Using virtual reality to understand how attention affects tobacco addiction

    This study is looking at how daily tobacco users react to virtual reality situations that remind them of smoking, to see if their attention to these cues can help predict how well they might do with quitting smoking, especially when using a medication called varenicline compared to a placebo.

    NIH research University of California, San Diego · La Jolla, United States · NIH-11164800

  • A program to help individuals with bipolar disorder reduce tobacco use through future thinking.

    This study is testing a new program called 'Future Self-BD' to help people with bipolar disorder who want to quit smoking by imagining positive future outcomes from stopping, and it aims to see how well the program works and if it's easy to use.

    NIH research Massachusetts General Hospital · Boston, United States · NIH-11077784

  • Using focused ultrasound to help people quit smoking

    This study is looking at a new, gentle ultrasound treatment that might help people who want to quit smoking by reducing their cravings for cigarettes, and it's designed for anyone struggling with tobacco use.

    NIH research U.s. Dept/vets Affairs Medical Center · Washington, United States · NIH-11070401

  • Improving health outcomes for people with opioid and tobacco use disorders

    This study is all about finding better ways to help people who are dealing with opioid and tobacco addiction, while also training new researchers from diverse backgrounds to make sure their work really helps those in need.

    NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11060946

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.