NIH-funded research R01 grant

Justice Core: Helping pregnant women with substance use get treatment while in jail

Official title: Justice Core: Effectiveness of a Jail Diversion Intervention for Pregnant Women with Substance Use Disorder

Funded at Univ of North Carolina Chapel Hill · NIH-11449160 · Data updated 2026-11-12

A pragmatic trial will test whether a jail diversion program (Justice Core) improves access to treatment and perinatal outcomes for pregnant women with substance use issues compared to usual referral after jail release.

More Substance Use research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startJuly 15, 2026
Project endApril 30, 2031
Funding year2026
Award (this year)$699,748
NIH project number1R01DA063702-01A1
Project IDNIH-11449160 on NIH RePORTER

Who could benefit from this research

Could help

Pregnant women (age 21+) with substance use disorder who are eligible for diversion from participating jails in North Carolina.

Less likely to help

Women without a substance use disorder or who are not in jail diversion pathways may not benefit from this specific program.

What this research studies

If you’re a pregnant woman with a substance use disorder and you’re in jail, Justice Core offers a structured assessment, tailored treatment recommendations, and help connecting you to community care before you’re released. The study will randomly assign about 300 participants from six North Carolina jails to either the Justice Core pathway or standard referral to treatment after release. Researchers will measure treatment engagement, relapse risk, and perinatal outcomes to see if this approach keeps mothers and babies healthier. This work is designed to identify practical steps that prisons can take to support effective treatment and safer births.

Why it matters

Potential benefit: If successful, the program could make SUD treatment during pregnancy more accessible and reduce poor birth outcomes and overdose risk after release.

How similar studies have gone: Prior research supports the idea that structured diversion and treatment linkage can improve outcomes, but this pragmatic trial will test effectiveness in real jail settings.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Knittel, Andrea Kathleen — Univ of North Carolina Chapel Hill
  • Study coordinator: Knittel, Andrea Kathleen

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.