Circadian rhythms and sleep for better blood sugar and heart health in adults with type 1 diabetes
Official title: Circadian Mechanisms of Glycemic Control and Cardiovascular Risk in Adults with Type 1 Diabetes
Funded at University of Illinois at Chicago · NIH-11418350 · Data updated 2026-11-12
A study tests whether improving sleep duration and regularity can help adults with type 1 diabetes control blood sugar and lower heart-disease risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Chicago NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project start | September 15, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $654,177 |
| NIH project number | 5R01HL174738-03 |
| Project ID | NIH-11418350 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults (21+ years) with type 1 diabetes who experience irregular sleep or short sleep duration and are able to participate in behavioral sleep interventions.
✕Less likely to help
Individuals unable to participate in sleep interventions or who have sleep disorders requiring medical treatment may not benefit.
What this research studies
This project focuses on adults with type 1 diabetes and investigates how sleep patterns affect blood sugar control and cardiovascular risk. The researchers will use behavioral sleep interventions to improve sleep duration and regularity and will monitor effects on glycemic measures and blood pressure patterns. By linking sleep improvements to glucose data from devices and cardiovascular risk markers, the study aims to uncover mechanisms behind sleep-related health benefits. Participants will engage in sleep programs and provide data through wearables, CGM readings, and clinical assessments overseen by the University of Illinois at Chicago team.
Why it matters
Potential benefit: If successful, people with type 1 diabetes could experience better blood sugar control and lower risk of cardiovascular problems through improved sleep habits.
How similar studies have gone: Preliminary studies show that behavioral sleep improvements can enhance glycemic parameters in type 1 diabetes, but the mechanisms are not fully understood.
Where this research is happening
-
University of Illinois at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Martyn-Nemeth, Pamela Ann — University of Illinois at Chicago
- Study coordinator: Martyn-Nemeth, Pamela Ann
Related research
Other NIH-funded projects on the same topics.
-
Cholesterol lowering and heart risk in adults with type 1 diabetes
This project tests how heart-healthy cholesterol reduction affects blood vessels in adults with type 1 diabetes to help prevent heart disease.
-
Sleep timing, blood sugar control, and heart health in adults with type 1 diabetes
This project looks at whether making sleep longer and more regular helps adults with type 1 diabetes keep blood sugar steadier and reduce heart disease risk.
-
Lowering cholesterol to protect heart health in Type 1 diabetes
People with Type 1 diabetes will take strong cholesterol‑lowering medicines for one month to find out if they reduce blood inflammation and help damaged arteries heal.
-
How sleep affects blood sugar control and heart health in adults with type 1 diabetes
This study is looking at how getting better sleep can help adults with type 1 diabetes manage their blood sugar levels and stay healthier, so if you struggle with sleep and diabetes, this research might be for you!
-
Investigating cholesterol reduction and heart disease risk in Type 1 diabetes
This study is looking at how lowering LDL cholesterol can help heart health in people with Type 1 diabetes, and it’s inviting participants from different communities in New York City to try out cholesterol-lowering treatments for four weeks to see how their bodies respond.
-
Technological and Educational Approaches to Restore Hypoglycemia Awareness in Type 1 Diabetes
A two-arm study in adults with type 1 diabetes tests whether high-tech glucose control plus education or targeted training can help people regain awareness of low blood sugar.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.