NIH-funded research R01 grant

Sleep timing, blood sugar control, and heart health in adults with type 1 diabetes

Official title: Circadian Mechanisms of Glycemic Control and Cardiovascular Risk in Adults with Type 1 Diabetes

Funded at University of Illinois at Chicago · NIH-11190878 · Data updated 2026-11-12

This project looks at whether making sleep longer and more regular helps adults with type 1 diabetes keep blood sugar steadier and reduce heart disease risk.

More Diabetes research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Chicago
NIH-funded
Lab location1 site (Chicago, UNITED STATES)
Project startSeptember 15, 2024
Project endAugust 31, 2029
Funding year2025
Award (this year)$658,710
NIH project number5R01HL174738-02
Project IDNIH-11190878 on NIH RePORTER

Who could benefit from this research

Could help

Adults (about 21 years and older) living with type 1 diabetes, especially those with short, irregular, or poor-quality sleep, are ideal candidates.

Less likely to help

People without type 1 diabetes or those who already have regular, sufficient sleep are unlikely to gain direct benefit from this specific project.

What this research studies

You would track your sleep and blood sugar while researchers measure blood pressure patterns and sleep-related hormones. Participants may wear a sleep monitor and a continuous glucose monitor, give urine or blood samples for melatonin metabolites, and have 24-hour blood pressure measurements. The team will offer a behavioral program to lengthen and regularize sleep and compare glucose control and cardiovascular risk markers before and after the program. The approach aims to show how improving sleep could lead to safer blood sugars and lower heart disease risk for people with T1D.

Why it matters

Potential benefit: If successful, this work could show that simple sleep changes help people with T1D manage glucose better and lower their cardiovascular risk.

How similar studies have gone: Earlier pilot studies and trials have shown that behavioral sleep interventions can improve sleep regularity and time spent in target glucose range, though the links to cardiovascular risk remain to be clarified.

Where this research is happening

  • University of Illinois at Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Martyn-Nemeth, Pamela Ann — University of Illinois at Chicago
  • Study coordinator: Martyn-Nemeth, Pamela Ann

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.