Changes in blood vessel structure after a stroke
Official title: Dynamic cerebrovascular morphology changes in acute ischemic stroke
Funded at University of California Riverside · NIH-11076680 · Data updated 2026-11-12
This study looks at how blood vessels in the brain change after a stroke and how different treatments can help restore blood flow, with the goal of better understanding recovery and improving care for stroke patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Riverside NIH-funded |
| Lab location | 1 site (Riverside, United States) |
| Project start | April 19, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $545,277 |
| NIH project number | 5R01NS131554-02 |
| Project ID | NIH-11076680 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced an acute ischemic stroke and are undergoing reperfusion therapy.
✕Less likely to help
Patients who have not experienced a stroke or those with other types of strokes may not benefit from this research.
What this research studies
This research investigates how the structure of blood vessels in the brain changes after an acute ischemic stroke and the effects of treatments that restore blood flow. By analyzing these changes, the study aims to improve predictions about patient outcomes following stroke and treatment. The researchers will use advanced imaging techniques to assess the morphology of cerebrovascular structures and develop predictive models that can guide treatment decisions. This work is crucial for enhancing the understanding of stroke recovery and optimizing patient care.
Why it matters
Potential benefit: If successful, this research could lead to better prediction of stroke outcomes and more effective treatment strategies for patients.
How similar studies have gone: Previous research has shown promise in using cerebrovascular morphology to predict outcomes in stroke patients, indicating that this approach may yield valuable insights.
Where this research is happening
-
University of California Riverside
Riverside, United States Active
Researchers
- Principal investigator: Laksari, Kaveh — University of California Riverside
- Study coordinator: Laksari, Kaveh
Related research
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A Mayo Clinic team is testing a nanoparticle-delivered tPA approach to help dissolve clots more effectively in people with acute ischemic stroke due to large vessel blockage.
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Aims to develop quick MRI techniques to identify tissue at risk in acute ischemic stroke and help decide whether to use advanced clot-busting treatment.
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Circadian factors shaping reperfusion success in acute stroke
This grant looks at how the body’s internal clock might influence how well stroke patients respond to clot-busting or clot-removal treatments.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.