Cannabis Use Disorder and Opioid Health Risks in Veterans: A Long-Term VA Study
Official title: The Impact of Cannabis Use Disorder and its Treatment on Opioid-related Health Consequences: A Longitudinal Study of VA Patients
Funded at Columbia University Health Sciences · NIH-11415661 · Data updated 2026-11-12
A long-term study of veterans looking at how cannabis use disorder and its treatment relate to opioid-related health problems and hospital visits.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 15, 2025 |
| Project end | May 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $708,556 |
| NIH project number | 5R01DA064130-02 |
| Project ID | NIH-11415661 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults in the VA system with cannabis use disorder and/or opioid-related health concerns who could benefit from improved treatment strategies.
✕Less likely to help
Individuals without cannabis use disorder or opioid-related health risks may not directly benefit from this study.
What this research studies
This project follows adult Veterans Affairs patients over time to understand how cannabis use disorder affects opioid-related hospitalizations, overdoses, and treatment outcomes. It will examine whether receiving treatment for cannabis use disorder changes these opioid-related risks. Researchers will analyze medical records from the VA to identify patterns and potential protective or harmful effects of CUD treatment on opioid health outcomes. The study aims to inform policies and care approaches within the VA to improve safety and health for people with both conditions.
Why it matters
Potential benefit: If successful, results could guide better integrated care for patients with cannabis use disorder and opioid-related health risks within VA healthcare.
How similar studies have gone: There is limited longitudinal evidence on CUD's impact on opioid outcomes; this study addresses a gap with large VA data.
Where this research is happening
-
Columbia University Health Sciences
New York, United States Active
Researchers
- Principal investigator: Mannes, Zachary L — Columbia University Health Sciences
- Study coordinator: Mannes, Zachary L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.