NIH-funded research R01 grant

Cannabis Use Disorder and Opioid Health Risks in Veterans: A Long-Term VA Study

Official title: The Impact of Cannabis Use Disorder and its Treatment on Opioid-related Health Consequences: A Longitudinal Study of VA Patients

Funded at Columbia University Health Sciences · NIH-11415661 · Data updated 2026-11-12

A long-term study of veterans looking at how cannabis use disorder and its treatment relate to opioid-related health problems and hospital visits.

More Cannabis research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences
NIH-funded
Lab location1 site (New York, United States)
Project startSeptember 15, 2025
Project endMay 31, 2030
Funding year2026
Award (this year)$708,556
NIH project number5R01DA064130-02
Project IDNIH-11415661 on NIH RePORTER

Who could benefit from this research

Could help

Adults in the VA system with cannabis use disorder and/or opioid-related health concerns who could benefit from improved treatment strategies.

Less likely to help

Individuals without cannabis use disorder or opioid-related health risks may not directly benefit from this study.

What this research studies

This project follows adult Veterans Affairs patients over time to understand how cannabis use disorder affects opioid-related hospitalizations, overdoses, and treatment outcomes. It will examine whether receiving treatment for cannabis use disorder changes these opioid-related risks. Researchers will analyze medical records from the VA to identify patterns and potential protective or harmful effects of CUD treatment on opioid health outcomes. The study aims to inform policies and care approaches within the VA to improve safety and health for people with both conditions.

Why it matters

Potential benefit: If successful, results could guide better integrated care for patients with cannabis use disorder and opioid-related health risks within VA healthcare.

How similar studies have gone: There is limited longitudinal evidence on CUD's impact on opioid outcomes; this study addresses a gap with large VA data.

Where this research is happening

  • Columbia University Health Sciences
    New York, United States
    Active

Researchers

  • Principal investigator: Mannes, Zachary L — Columbia University Health Sciences
  • Study coordinator: Mannes, Zachary L

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.