NIH-funded research U01 cooperative agreement

BSMART: HIV care-integrated smoking cessation program

Official title: Botswana Smoking Abstinence Reinforcement Trial (BSMART)

Funded at University of Maryland Baltimore · NIH-11401178 · Data updated 2026-11-12

A program to help people living with HIV quit smoking using a proven 5A brief intervention plus support and medication within HIV clinics.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Maryland Baltimore
NIH-funded
Lab location1 site (Baltimore, United States)
Project startSeptember 15, 2022
Project endAugust 31, 2027
Funding year2026
Award (this year)$463,578
NIH project number5U01CA275048-05
Project IDNIH-11401178 on NIH RePORTER

Who could benefit from this research

Could help

Adults living with HIV/AIDS who smoke and are receiving care at participating HIV clinics.

Less likely to help

Individuals who do not smoke or who cannot participate in the clinic-based program may not receive a direct benefit.

What this research studies

This project tests a real-world approach to helping people living with HIV quit smoking by embedding a simple counseling method (the 5As) and providing varenicline through nurse prescribers at HIV care sites. It uses a hybrid design to see both how well the program works and how easily clinics can implement it in routine care. The plan includes training lay workers to deliver the intervention, monitoring quality, and evaluating costs to support potential widespread adoption.

Why it matters

Potential benefit: If successful, this program could reduce smoking-related illnesses and improve overall health for people living with HIV.

How similar studies have gone: Previous smoking-cessation strategies in HIV care have shown benefit, but this study tests an integrated, real-world implementation approach.

Where this research is happening

  • University of Maryland Baltimore
    Baltimore, United States
    Active

Researchers

  • Principal investigator: Charurat, Manhattan E — University of Maryland Baltimore
  • Study coordinator: Charurat, Manhattan E

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.