NIH-funded research R01 grant

Automated chest X-ray reading for diagnosing childhood TB (AI for kids and HIV)

Official title: The development and expansion of automated chest x-ray reading algorithms for childhood tuberculosis

Funded at University of California, San Francisco · NIH-11565120 · Data updated 2026-11-12

A pediatric-focused AI tool is being developed to read chest X-rays and help screen, diagnose, and guide treatment for children with TB, including those living with HIV.

More Tuberculosis research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco
NIH-funded
Lab location1 site (San Francisco, United States)
Project startSeptember 1, 2026
Project endMay 31, 2030
Funding year2026
Award (this year)$183,488
NIH project number3R01HL184914-01S1
Project IDNIH-11565120 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are children and adolescents including those with HIV who are undergoing evaluation for pulmonary TB and have chest X-rays.

Less likely to help

Children without suspected TB or without access to chest X-ray evaluation may not benefit.

What this research studies

This project aims to adapt and test computer-aided reading of pediatric chest X-rays to improve detection and management of tuberculosis in children, especially those with HIV. Researchers will fine-tune AI models on pediatric X-ray images to support decisions about screening, diagnosis, and how long to treat. The study will evaluate accuracy, safety, and usefulness of the AI tool in real-world pediatric settings. If successful, this technology could reduce missed TB cases and shorten time to treatment for children.

Why it matters

Potential benefit: If successful, children could receive quicker and more accurate TB screening and treatment decisions.

How similar studies have gone: AI tools for adult TB screening exist, but this project focuses on validating and adapting them for children, which is novel and more challenging.

Where this research is happening

  • University of California, San Francisco
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Jaganath, Devan — University of California, San Francisco
  • Study coordinator: Jaganath, Devan

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.