Aberrant glycogen in lung adenocarcinoma tumor growth
Official title: Aberrant Glycogen in Lung Adenocarcinoma Tumorigenesis
Funded at University of Florida · NIH-11350893 · Data updated 2026-11-12
A new project will study how abnormal glycogen in lung adenocarcinoma tumors may drive cancer growth and help identify targets for future therapies.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | July 1, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $518,696 |
| NIH project number | 5R01CA266004-06 |
| Project ID | NIH-11350893 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with lung adenocarcinoma, particularly those undergoing tissue analysis to understand tumor biology.
✕Less likely to help
Patients without LUAD or those whose tumors do not show the glycogen phenotype may not benefit from this specific focus.
What this research studies
This research focuses on understanding why lung adenocarcinoma tumors accumulate abnormal glycogen and how this might promote tumor progression. The team has developed a sensitive technique to visualize glycogen in tumor tissue, enabling precise mapping of glycogen patterns in samples from lung cancer patients. By comparing LUAD tissues to normal lung and other lung cancers, scientists aim to pinpoint glycogen-related changes that could become targets for personalized treatment strategies. The work builds on prior findings showing LUAD-specific glycogen features and seeks to translate these insights into potential biomarkers or therapeutic approaches.
Why it matters
Potential benefit: If successful, the study could identify glycogen-related markers or targets that lead to more effective, personalized treatments for LUAD patients.
How similar studies have gone: Preliminary data suggest LUAD-specific glycogen features, indicating potential for meaningful progress with this approach.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Sun, Ramon C. — University of Florida
- Study coordinator: Sun, Ramon C.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.