NIH-funded research R01 grant

A new approach to help adults who aren’t ready to quit start quitting more often

Official title: A Novel Intervention to Increase Smoking Quit Attempts and Cessation among Adults Initially Unready to Quit

Funded at University of Oklahoma Hlth Sciences Ctr · NIH-11432918 · Data updated 2026-11-12

A health intervention uses tailored daily messages to motivate and support adults who aren’t ready to quit smoking, helping them make quit attempts and stay abstinent.

More Smoking research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Oklahoma Hlth Sciences Ctr
NIH-funded
Lab location1 site (Oklahoma City, United States)
Project startAugust 1, 2026
Project endJuly 31, 2031
Funding year2026
Award (this year)$606,142
NIH project number1R01CA315811-01
Project IDNIH-11432918 on NIH RePORTER

Who could benefit from this research

Could help

Adults 21 years or older who smoke and are not currently ready to quit within 30 days, willing to receive daily messages and engage with cessation resources.

Less likely to help

Individuals who are ready to quit immediately or who do not engage with mobile messaging may be less likely to benefit.

What this research studies

This program builds on a prior trial that used two daily messages tailored to a person’s readiness to quit. It aims to increase quit attempts and smoking abstinence by delivering phase-based, motivational content and coping strategies. Participants can access smoking-cessation resources with one click when they set a quit date. The study is conducted with adults 21+ who smoke and are not yet ready to quit within 30 days, across multiple groups including a tailoring approach and a control condition.

Why it matters

Potential benefit: If successful, this approach could provide a scalable way to help more smokers start quitting and stay smoke-free.

How similar studies have gone: Prior Phoenix pilot showed feasibility and potential benefit with phase-based messaging in a similar population.

Where this research is happening

  • University of Oklahoma Hlth Sciences Ctr
    Oklahoma City, United States
    Active

Researchers

  • Principal investigator: Businelle, Michael S. — University of Oklahoma Hlth Sciences Ctr
  • Study coordinator: Businelle, Michael S.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.