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Total Neoadjuvant Treatment clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Total Neoadjuvant Treatment clinical trials that are recruiting, at sites in 3 countries (most in Taiwan (1), Lithuania (1), China (1)). By phase: Phase 2 (2), Phase 2/3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 3Countries
Newest Total Neoadjuvant Treatment clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Short-course pelvic radiotherapy followed by CAPOX (capecitabine + oxaliplatin) and bevacizumab, with or without PD‑1 immunotherapy, for locally advanced rectal cancer. | Phase 2 | Shanghai | Recruiting | Sep 30, 2025 |
| Neoadjuvant immunochemotherapy and chemoradiotherapy before surgery for advanced esophageal squamous cell carcinoma | Phase 2 | Taipei | Recruiting | Jan 8, 2025 |
| Comparing total neoadjuvant therapy with surgery for rectal cancer treatment | Phase 2/3 | Vilnius | Recruiting | Jan 6, 2025 |
All recruiting trials (3)
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Short-course pelvic radiotherapy followed by CAPOX (capecitabine + oxaliplatin) and bevacizumab, with or without PD‑1 immunotherapy, for locally advanced rectal cancer.
This trial tests whether adding a PD‑1 immunotherapy to short-course radiotherapy followed by CAPOX and bevacizumab helps adults with locally advanced rectal cancer get a higher complete response rate and fewer distant metastases.
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Neoadjuvant immunochemotherapy and chemoradiotherapy before surgery for advanced esophageal squamous cell carcinoma
This study tests whether giving the immune drug tislelizumab with chemotherapy before and then combining chemoradiotherapy, followed by surgery, helps people with locally advanced esophageal squamous cell carcinoma.
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Comparing total neoadjuvant therapy with surgery for rectal cancer treatment
This study is testing if rectal cancer patients who respond well to a new treatment can skip surgery and just be monitored to see how they do compared to those who have surgery right away.
Related topics
Quick answers
How many Total Neoadjuvant Treatment clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in Taiwan (1 trial), Lithuania (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.