Condition

Severe Aplastic Anemia clinical trials and research

• 14Clinical trials
• 3NIH research projects
• 2Countries

Newest Severe Aplastic Anemia clinical trials

All recruiting trials (14)

• BFCA conditioning for Haplo-HSCT in older adults with severe aplastic anemia

  This study tests the BFCA conditioning regimen in adults aged 40–60 with severe aplastic anemia undergoing haploidentical stem cell transplant to see if it’s safe and effective.

  Recruiting Peking University People's Hospital · Beijing, Beijing Municipality · NCT07586735

• Bone marrow transplant for severe aplastic anemia

  This study is testing if bone marrow transplants from partially matched or unrelated donors can help people aged 3 to 75 with severe aplastic anemia who haven't had treatment before.

  Recruiting at 25 sites Phase 2 Medical College of Wisconsin · Birmingham, Alabama and 24 other locations · NCT06517641

• Hematopoietic cell transplant for severe blood disorders

  This study is testing a new way to prepare patients with severe blood disorders for a stem cell transplant to see if it can improve their recovery and reduce complications.

  Recruiting Phase 2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT06412497

• Modified stem cell transplantation for severe aplastic anemia

  This study is testing a new way of doing stem cell transplants for people with severe aplastic anemia to see if it can help them live longer and reduce complications.

  Recruiting Phase 2 Hematology department of the 920th hospital · Kunming, Yunnan · NCT06378060

• Using Rituximab to treat severe aplastic anemia with platelet transfusion issues

  This study is testing if rituximab can help people with severe aplastic anemia who have trouble getting enough platelets from transfusions.

  Recruiting Phase 2 Institute of Hematology & Blood Diseases Hospital, China · Tianjin, Tianjin Municipality · NCT06254560

• Understanding long-term effects of bone marrow failure syndromes

  This study is looking at how bone marrow failure syndromes affect people over time to see how the disease and treatments change, focusing on individuals aged 2 and older.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT05012111

• Haploidentical stem cell transplant for treating blood disorders in children

  This study is testing a new way to use stem cell transplants from partially matched family members to help children with serious blood disorders feel better when other treatments haven't worked.

  Recruiting Phase 2 Johns Hopkins All Children's Hospital · St. Petersburg, Florida · NCT04356469

• Early treatment for severe aplastic anemia using cyclosporine and eltrombopag

  This study is testing if starting treatment for severe aplastic anemia with a mix of lower doses of cyclosporine and eltrombopag can help patients recover their blood counts faster.

  Recruiting Phase 2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT04304820

• Stem cell transplantation for blood disorders using specific cell depletion techniques

  This study is testing a new way of using stem cell transplants for children and young adults with blood disorders to see if removing certain cells helps them recover better and improve their quality of life.

  Recruiting Phase 2 New York Medical College · Valhalla, New York · NCT04099966

• Transplantation for inherited bone marrow failure disorders

  This study is testing a new way to do stem cell transplants for people with inherited bone marrow failure disorders to see if it can help them recover faster and reduce the risk of infections without needing extra medication.

  Recruiting Phase 2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT03579875

• Using umbilical cord blood to improve transplant outcomes for severe blood disorders

  This study is testing whether using a mix of blood stem cells from a family member and umbilical cord blood can help improve transplant success for people aged 4-60 with severe blood disorders like aplastic anemia and myelodysplastic syndrome.

  Recruiting Phase 1/2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT03173937

• Haploidentical bone marrow transplant for severe aplastic anemia

  This study is testing if a special type of bone marrow transplant from a mismatched donor can help people with severe aplastic anemia who don't have a matching donor.

  Recruiting at 2 sites Phase 2 Northside Hospital, Inc. · Atlanta, Georgia and 1 other locations · NCT02828592

• Access and distribution of unlicensed cryopreserved cord blood units

  This study is testing how well unlicensed frozen cord blood units work for helping both kids and adults with blood cancers recover after a transplant.

  Recruiting at 113 sites Center for International Blood and Marrow Transplant Research · Birmingham, Alabama and 141 other locations · NCT01351545

• Transplanting stem cells to treat severe blood disorders

  This study is testing a new way to use stem cells for treating severe blood disorders to see if it can reduce complications and improve outcomes for patients with conditions like severe aplastic anemia.

  Recruiting Phase 2 National Institutes of Health Clinical Center (CC) · Baltimore, Maryland and 1 other locations · NCT01174108

NIH-funded research (3)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Clinical and immunologic study of pediatric severe aplastic anemia to personalize care

  A pediatric-focused research effort will collect and study immune and clinical data to tailor treatments for children with severe aplastic anemia.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11453341

• Comparing bone marrow transplantation with immune therapy for severe aplastic anemia in young patients

  This study is looking at whether bone marrow transplants from unrelated donors or immune suppression therapy works better for kids and young adults with newly diagnosed severe aplastic anemia, especially since not everyone has a sibling who can donate bone marrow.

  NIH research Medical College of Wisconsin · Milwaukee, United States · NIH-11060990

• Comparing bone marrow transplantation and immune suppression therapy for severe aplastic anemia in young patients

  This study is looking at whether getting a bone marrow transplant from an unrelated donor or using immune suppression therapy works better for kids and young adults who have just been diagnosed with severe aplastic anemia, especially since not everyone has a matched sibling donor.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11060911

Related topics

Quick answers

How many Severe Aplastic Anemia clinical trials are recruiting right now?

14, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (11 trials), China (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 10, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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