Giving surfactant to premature infants using a thin catheter at birth

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to determine if administering surfactant through a thin endotracheal catheter to extremely premature infants shortly after birth can reduce the need for mechanical ventilation within the first 72 hours of life. Infants born before 28 weeks of gestation who are receiving breathing support will be randomly assigned to receive surfactant via a thin catheter or continue with face mask support. The study will closely monitor the infants to assess the impact of this method on their respiratory outcomes.

Why it matters

Who can join: the full rules

Inclusion criteria

* Infants of any sex born before 28 weeks of gestation
* Clinicians plan to provide intensive care
* Consent for their participation provided by parent(s)/guardian(s) before their birth

Exclusion criteria

• Major congenital anomalies (e.g. upper airway anomaly, diaphragmatic hernia, gastroschisis, exomphalos major, intestinal atresias, open neural tube defect, aneuploidy, cardiac lesions other than ASD/PFO/VSD/PDA )

Where it's running

• National Maternity Hospital
  Dublin, None Selected, Ireland Recruiting

Study contacts

• Principal investigator: Colm PF O'Donnell — National Maternity Hospital, University College Dublin
• Study coordinator: Colm PF O'Donnell, MB PhD
• Email: codonnell@nmh.ie
• Phone: 35316373100

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.