Condition

Renal Impairment clinical trials and research

• 10Clinical trials
• 7Countries

Newest Renal Impairment clinical trials

All recruiting trials (10)

• Rilzabrutinib in adults with severe kidney impairment vs. normal kidney function

  This study tests how rilzabrutinib behaves in the body and its safety in adults with severe kidney impairment compared to healthy adults.

  Recruiting Phase 1 Sanofi · Hialeah, Florida · NCT07853131

• Ribupatide PK in People with Kidney Impairment

  This study tests how a single shot of ribupatide behaves in the body for people with severe kidney problems compared to those with normal kidney function.

  Recruiting at 2 sites Phase 1 Kailera · Orlando, Florida and 1 other locations · NCT07793929

• Renal function and afabicin; how kidney health changes drug levels

  This trial tests how different levels of kidney function affect the blood levels of afabicin given as a pill or IV after a single dose.

  Recruiting Phase 1 Debiopharm International SA · Berlin · NCT07758608

• Safety and how the body handles RO7795081 in people with kidney problems

  This study tests how RO7795081 behaves in the body and its safety after a single dose in people with normal kidney function and those with renal impairment.

  Recruiting at 3 sites Phase 1 Hoffmann-La Roche · Miami Lakes, Florida and 2 other locations · NCT07741604

• Testing D-2570 in adults with varying kidney function

  This study tests a single dose of D-2570 in adults aged 18–70 with different levels of kidney function to see how the drug behaves in the body.

  Recruiting Phase 1 InventisBio Co., Ltd · Hefei, Anhui · NCT07715175

• Safety and blood levels of INCB123667 in adults with severe kidney problems

  This study tests whether oral INCB123667 is safe and how it behaves in the body for adults with severe renal impairment or end-stage kidney disease.

  Recruiting at 2 sites Phase 1 Incyte Corporation · Miami Lakes, Florida and 1 other locations · NCT07559396

• How the body processes PF-07328948 in people with normal or reduced kidney function

  We will give a single oral dose of PF-07328948 to adults with normal or moderately-to-severely reduced kidney function to see how their bodies process the medicine and how well they tolerate it.

  Recruiting at 4 sites Phase 1 Pfizer · Lake Forest, California and 3 other locations · NCT07315360

• Renal assist device to protect kidney function during on-pump heart surgery

  This study will try a temporary Renal Assist Device during on-pump coronary artery bypass or valve surgery to help adults with weakened kidneys (eGFR 15–60) keep kidney function after the operation.

  Recruiting at 6 sites 3ive Labs · Weston, Florida and 6 other locations · NCT07017933

• Assessing the safety and pharmacokinetics of rupatadine in patients with renal impairment

  This study is testing how well the allergy medication rupatadine works and is tolerated in people with kidney problems compared to those with healthy kidneys.

  Recruiting at 7 sites Phase 1 Noucor Health S.A. · Gaia and 6 other locations · NCT06708520

• Identifying biomarkers to predict kidney injury in diabetic patients

  This study is testing if certain markers in blood and urine can help predict kidney injury in diabetic patients who are at risk during procedures using contrast dye.

  Recruiting Barts & The London NHS Trust · London · NCT00948116

Related topics

Quick answers

How many Renal Impairment clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (6 trials), United Kingdom (1 trial), Portugal (1 trial), Spain (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 8. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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