Drug or treatment

Rilzabrutinib clinical trials

• 7Clinical trials
• 31Countries

Newest trials

All recruiting trials (7)

• Rilzabrutinib in adults with severe kidney impairment vs. normal kidney function

  This study tests how rilzabrutinib behaves in the body and its safety in adults with severe kidney impairment compared to healthy adults.

  Recruiting Phase 1 Sanofi · Hialeah, Florida · NCT07853131

• Rilzabrutinib versus placebo for adults with IgG4-related disease (52-week treatment)

  This 52-week study will try rilzabrutinib tablets to see if they prevent disease flares and better control symptoms in adults with active IgG4-related disease compared with placebo.

  Recruiting at 91 sites Phase 3 Sanofi · Fontana, California and 94 other locations · NCT07190196

• Oral rilzabrutinib versus placebo for adults with warm autoimmune hemolytic anemia

  This trial tests whether the oral drug rilzabrutinib can raise and sustain hemoglobin better than placebo in adults with primary warm autoimmune hemolytic anemia who have not had lasting benefit from steroids.

  Recruiting at 105 sites Phase 3 Sanofi · Phoenix, Arizona and 104 other locations · NCT07086976

• Oral rilzabrutinib for adults with immune thrombocytopenia after first-line treatment fails.

  This study will test whether the oral drug rilzabrutinib can raise and keep platelet counts up in adults with ITP who did not have lasting benefit from first-line therapy.

  Recruiting at 36 sites Phase 3 Sanofi · Clovis, California and 35 other locations · NCT07007962

• Rilzabrutinib treatment for adults with Graves' disease

  This trial will test two doses of the oral drug rilzabrutinib in adults with Graves' disease, with or without Graves' orbitopathy, to see which dose better controls hyperthyroidism and is safe.

  Recruiting at 19 sites Phase 2 Sanofi · Buenos Aires and 23 other locations · NCT06984627

• Evaluating Rilzabrutinib for Sickle Cell Disease in Patients Aged 10 to 65

  This study is testing a new medication called rilzabrutinib to see if it can help people aged 10 to 65 with sickle cell disease have fewer pain crises and improve their overall health.

  Recruiting at 63 sites Phase 3 Sanofi · Birmingham, Alabama and 62 other locations · NCT06975865

• Evaluating treatments for kidney diseases in young to middle-aged adults

  This study is testing three different treatments for kidney diseases in young to middle-aged adults to see if they can reduce protein levels in urine and help with symptoms over 24 weeks.

  Recruiting at 78 sites Phase 2 Sanofi · Birmingham, Alabama and 78 other locations · NCT06500702

Quick answers

How many clinical trials of Rilzabrutinib are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 31 countries. The most sites are in United States (6 trials), Germany (6 trials), Italy (6 trials), Spain (6 trials), Argentina (4 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 4, Phase 2: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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