Condition

Recurrent Malignant Solid Neoplasm clinical trials and research

• 13Clinical trials
• 4Countries

Newest Recurrent Malignant Solid Neoplasm clinical trials

All recruiting trials (13)

• Predicting how tumors respond to immune therapies using a live diagnostic platform

  This study is testing a new way to predict how well immune therapies will work for patients with different types of solid tumors, including early-stage and metastatic cancers.

  Recruiting at 3 sites Mayo Clinic · Phoenix, Arizona and 2 other locations · NCT06349642

• Combining axatilimab, retifanlimab, and paclitaxel for advanced solid tumors

  This study is testing a new combination of three medications to see if they can help people with advanced solid tumors feel better and improve their treatment outcomes.

  Recruiting Phase 1/2 OHSU Knight Cancer Institute · Portland, Oregon · NCT06320405

• Investigating blood cancer risks in patients with ovarian and other solid tumors

  This study is trying to see if certain cancer treatments for ovarian and other solid tumors can increase the risk of blood cancers in patients.

  Recruiting University of Washington · Seattle, Washington · NCT06295965

• Evaluating TAK-243 for advanced cancer treatment

  This study is testing a new drug called TAK-243 to see if it can safely help people with advanced cancer by looking at how it affects their tumors and overall health.

  Recruiting Phase 1 National Cancer Institute (NCI) · Bethesda, Maryland · NCT06223542

• Testing neratinib alone or with palbociclib for HER2 positive solid tumors

  This study is testing if a new cancer treatment called neratinib works better alone or with another drug, palbociclib, for people with HER2 positive solid tumors, especially those with gynecologic cancers.

  Recruiting at 181 sites Phase 2 National Cancer Institute (NCI) · Birmingham, Alabama and 193 other locations · NCT06126276

• Targeted therapy for advanced solid tumors based on genetic testing

  This study is testing whether matching patients with advanced solid tumors to specific treatments based on their genetic makeup can improve their outcomes when standard options have failed.

  Recruiting at 437 sites Phase 2 National Cancer Institute (NCI) · Birmingham, Alabama and 483 other locations · NCT05564377

• Parenting support for families dealing with advanced cancer

  This study is testing a new parenting support program for families dealing with advanced cancer to see if it helps them cope better than standard care.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT05059678

• Onivyde combined with talazoparib or temozolomide for children and young adults with recurrent solid tumors and Ewing sarcoma

  This will test whether adding talazoparib or temozolomide to Onivyde helps children and young adults whose solid tumors or Ewing sarcoma have come back.

  Recruiting at 8 sites Phase 1/2 St. Jude Children's Research Hospital · Palo Alto, California and 9 other locations · NCT04901702

• CBL0137 treatment for relapsed or refractory solid tumors and CNS tumors

  This study is testing a new treatment called CBL0137 to see if it can help children and young adults with tough-to-treat solid tumors and brain tumors feel better.

  Recruiting at 33 sites Phase 1/2 Children's Oncology Group · Birmingham, Alabama and 34 other locations · NCT04870944

• Tegavivint treatment for recurrent or refractory solid tumors in children

  This study tests if a new intravenous medication called tegavivint can help children with tough-to-treat solid tumors, like Ewing sarcoma and desmoid tumors, by finding the right dose and seeing how well it works.

  Recruiting at 19 sites Phase 1/2 Children's Oncology Group · Birmingham, Alabama and 20 other locations · NCT04851119

• Combining talazoparib with palbociclib, axitinib, or crizotinib for advanced solid tumors

  This study is testing a new combination of drugs for people with advanced solid tumors to see which mix works best and is safest to use.

  Recruiting Phase 1 M.D. Anderson Cancer Center · Houston, Texas · NCT04693468

• Gene modified immune cells for treating advanced melanoma and metastatic solid tumors

  This study is testing if modified immune cells can safely target and attack advanced melanoma and other solid tumors in patients after they receive chemotherapy.

  Recruiting at 3 sites Phase 1 Stanford University · Duarte, California and 2 other locations · NCT04119024

• Collecting and storing tissue and blood samples from cancer patients

  This study is collecting and storing blood and tissue samples from cancer patients to help researchers create better models for understanding cancer and testing new treatments.

  Recruiting at 18 sites National Cancer Institute (NCI) · Birmingham, Alabama and 139 other locations · NCT02474160

Related topics

Quick answers

How many Recurrent Malignant Solid Neoplasm clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in United States (13 trials), Puerto Rico (2 trials), Canada (1 trial), Australia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 4, Phase 1: 3, Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →