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Rectal Cancer Stage II clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Rectal Cancer Stage II clinical trials that are recruiting, at sites in 3 countries (most in United States (2), China (2), Vietnam (1)). By phase: Phase 2 (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 3Countries
Newest Rectal Cancer Stage II clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Neoadjuvant mFOLFOX with Citrus Flavonoid Tablets for YWHAB-High Locally Advanced Rectal Cancer | Phase 2 | Guangzhou, Guangdong | Recruiting | Sep 16, 2025 |
| Meal timing during cancer treatment for Alaska Native and American Indian patients | — | Anchorage, Alaska | Recruiting | Jan 31, 2025 |
| Monitoring blood markers to predict treatment response in rectal cancer | — | Ho Chi Minh City | Recruiting | Sep 19, 2024 |
| Prehabilitation program for patients with rectal cancer | — | Boston, Massachusetts and 1 other locations | Recruiting | Aug 21, 2024 |
| Effects of Tislelizumab with Chemotherapy in Advanced Rectal Cancer | Phase 2 | Nanning, Guangxi | Recruiting | Feb 12, 2024 |
All recruiting trials (5)
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Neoadjuvant mFOLFOX with Citrus Flavonoid Tablets for YWHAB-High Locally Advanced Rectal Cancer
In people with locally advanced rectal cancer who have high YWHAB expression, this study tests whether adding citrus flavonoid tablets to a standard mFOLFOX neoadjuvant regimen helps shrink tumors before surgery.
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Meal timing during cancer treatment for Alaska Native and American Indian patients
This test will see if an 8-hour time-restricted eating schedule during neoadjuvant or adjuvant therapy helps Alaska Native and American Indian adults with rectal or certain breast cancers.
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Monitoring blood markers to predict treatment response in rectal cancer
This study is testing if measuring certain blood markers in patients with stage II and III rectal cancer can help predict how well they respond to treatment.
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Prehabilitation program for patients with rectal cancer
This study is testing a prehabilitation program to see if it helps people with rectal cancer feel better before surgery compared to standard care.
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Effects of Tislelizumab with Chemotherapy in Advanced Rectal Cancer
This study is testing if adding a new drug called Tislelizumab to chemotherapy can help people with advanced rectal cancer have better outcomes before surgery.
Related topics
Quick answers
How many Rectal Cancer Stage II clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (2 trials), China (2 trials), Vietnam (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.