Condition
Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH) clinical trials and research
As of November 12, 2026, Find a Trial lists 7 Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH) clinical trials that are recruiting, at sites in 4 countries (most in Brazil (4), United States (1), United Kingdom (1)). By phase: Phase 2/3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 7Clinical trials
- 4Countries
Newest Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH) clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Add-on Sildenafil Before Exercise in PAH to See if Max Workload Improves | Phase 2/3 | Zurich, Canton of Zurich | Recruiting | Sep 17, 2026 |
| Nailfold Capillaroscopy in Pulmonary Hypertension | — | Clydebank, West Dunbartonshire | Recruiting | Aug 17, 2026 |
| Rutgers Genetics of Pulmonary Hypertension | — | Piscataway, New Jersey | Recruiting | Oct 16, 2025 |
| Testing a patient questionnaire about pulmonary hypertension knowledge | — | São Paulo, São Paulo | Recruiting | Aug 13, 2025 |
| Switching endothelin receptor medicines and risk in pulmonary arterial hypertension | — | São Paulo, São Paulo | Recruiting | Jun 10, 2025 |
| Timing of pulmonary arterial hypertension diagnosis in Brazil | — | São Paulo, São Paulo | Recruiting | May 31, 2025 |
| Improving adherence to PAH treatment with telemedicine and patient guidance | — | São Paulo, São Paulo | Recruiting | Feb 27, 2025 |
All recruiting trials (7)
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Add-on Sildenafil Before Exercise in PAH to See if Max Workload Improves
This study tests whether taking 20 mg sildenafil right before exercise helps people with pulmonary arterial hypertension perform more work during cardiopulmonary testing.
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Nailfold Capillaroscopy in Pulmonary Hypertension
This study tests whether nailfold capillary scans correlate with invasive lung blood pressure measurements and whether these patterns change with PH treatment.
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Rutgers Genetics of Pulmonary Hypertension
This online project will try to see if genetic differences affect the risk of pulmonary hypertension in U.S. adults, and anyone 18 or older can join whether or not they have PH.
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Testing a patient questionnaire about pulmonary hypertension knowledge
This project will test a questionnaire to measure what adults with pulmonary arterial hypertension know about their condition, treatments, and self-care.
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Switching endothelin receptor medicines and risk in pulmonary arterial hypertension
This study will try switching adults with PAH from ambrisentan to bosentan to see if the change alters their clinical risk profile and liver safety.
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Timing of pulmonary arterial hypertension diagnosis in Brazil
We will see how long it takes adults with pulmonary arterial hypertension in Brazil to get a confirmed diagnosis and what causes delays.
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Improving adherence to PAH treatment with telemedicine and patient guidance
This study will try whether regular telemedicine check-ins and guided education help people with PAH stick to their oral medications and manage side effects.
Related topics
Quick answers
How many Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH) clinical trials are recruiting right now?
7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 4 countries. The most sites are in Brazil (4 trials), United States (1 trial), United Kingdom (1 trial), Switzerland (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.