Rutgers Genetics of Pulmonary Hypertension
Official title: Rutgers University Study of the Genetics of Pulmonary Hypertension
Run by Rutgers, The State University of New Jersey · NCT07217522 · Data updated 2026-11-12
This online project will try to see if genetic differences affect the risk of pulmonary hypertension in U.S. adults, and anyone 18 or older can join whether or not they have PH.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | Rutgers, The State University of New Jersey Academic / other |
| Locations | 1 site (Piscataway, New Jersey) |
| Status | Recruiting |
| Started | August 23, 2025 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | November 3, 2025 |
| Trial ID | NCT07217522 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal participants are adults (18+) living in the United States who can read English, access the internet, and are willing to complete online surveys and mail in a saliva DNA sample.
✕Probably not a fit
People under 18, non-U.S. residents, those unable to participate in English or without internet access, and anyone seeking immediate clinical treatment are unlikely to receive direct benefit from this research.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This online observational project collects short health surveys and a mailed saliva sample to study how genetic differences relate to pulmonary hypertension risk. Participation is remote, takes about 20 minutes, and does not require any clinic visits. Participants may optionally share electronic health records and can choose to receive genetic ancestry information at no cost. Investigators seek a diverse participant pool to make genetic findings more useful across populations.
Why it matters
Potential benefit: If successful, the project could identify genetic risk factors that help guide future screening, prevention, and treatment research for pulmonary hypertension.
How similar studies have gone: Previous genetic studies have found genes linked to familial PAH (for example BMPR2), but large, diverse population-based genetic efforts for pulmonary hypertension remain an active area of research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age 18 years or older * currently living in the United States * able to understand and follow written instructions in English * have access to the internet and a computer, laptop, tablet or smart phone * willing to provide written informed consent for participation * willing to provide DNA via a saliva sample using a collection kit mailed to the study participant's home * willing to complete a survey with questions about health related to the study of pulmonary hypertension. Exclusion Criteria: * Age 17 or below * Not currently living in the United States * Not able to participate in an online research study in English
Where it's running
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Rutgers University, Piscataway, New Jersey 08854
Piscataway, New Jersey, United States Recruiting
Study contacts
- Principal investigator: Tara Matise, Ph.D. — Rutgers, The State University of New Jersey
- Study coordinator: Tara Matise, Ph.D.
- Email: rugcc-ph@rutgers.edu
- Phone: 848-445-3125
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Improving adherence to PAH treatment with telemedicine and patient guidance
This study will try whether regular telemedicine check-ins and guided education help people with PAH stick to their oral medications and manage side effects.
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129Xe MRI to monitor sotatercept treatment in pulmonary arterial hypertension
This will test whether hyperpolarized 129Xe MRI scans can noninvasively track lung blood-vessel improvement in adults with pulmonary arterial hypertension treated with sotatercept.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.