Condition
PALB2 Gene Mutation clinical trials and research
As of November 12, 2026, Find a Trial lists 4 PALB2 Gene Mutation clinical trials that are recruiting, at sites in 2 countries (most in United States (3), United Kingdom (1)). By phase: Phase 1 (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 2Countries
Newest PALB2 Gene Mutation clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Combining niraparib and irinotecan for cancers with DNA repair gene mutations | Phase 1 | San Francisco, California | Recruiting | Jan 23, 2023 |
| Increasing Genetic Testing for Families at Risk of Cancer | — | Basking Ridge, New Jersey and 7 other locations | Recruiting | Jun 15, 2022 |
| Imaging study using FCH-PET-CT in men with prostate cancer and DNA repair gene mutations | — | London, Sutton, Surrey | Recruiting | Oct 28, 2021 |
| Treatment for metastatic cancer with BRCA or PALB2 mutations using chemotherapy and stem cells | Phase 1 | Boston, Massachusetts and 1 other locations | Recruiting | Nov 4, 2019 |
All recruiting trials (4)
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Combining niraparib and irinotecan for cancers with DNA repair gene mutations
This study is testing a new combination of two cancer drugs, niraparib and irinotecan, to see if it's safe and effective for people with certain types of cancer that have DNA repair gene mutations.
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Increasing Genetic Testing for Families at Risk of Cancer
This study is testing a new way to encourage families at risk of cancer to get genetic testing by having healthcare providers reach out directly to them instead of relying on patients to share their results.
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Imaging study using FCH-PET-CT in men with prostate cancer and DNA repair gene mutations
This study is testing if a new type of imaging called FCH-PET-CT can better find cancer spread in men with prostate cancer who have certain gene mutations compared to regular imaging methods.
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Treatment for metastatic cancer with BRCA or PALB2 mutations using chemotherapy and stem cells
This study is testing a new treatment combining chemotherapy and stem cells for people with metastatic pancreatic or breast cancer who have BRCA or PALB2 mutations to see if it is safe and effective.
Related topics
Quick answers
How many PALB2 Gene Mutation clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (3 trials), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.