Condition

Overweight and/or Obesity clinical trials and research

• 16Clinical trials
• 3New in 30 days
• 16Countries

Newest Overweight and/or Obesity clinical trials

All recruiting trials (16)

• Weekly berobenatide for knee osteoarthritis in adults who are overweight or obese

  This study tests whether weekly berobenatide helps reduce knee pain and improve function, while also affecting body weight, in adults with knee osteoarthritis who are overweight or obese (with or without type 2 diabetes).

  Recruiting Phase 3 Pfizer · Birmingham, Alabama and 3 other locations · NCT07915609

• Berobenatide in adults with sleep apnea and obesity who don’t use a PAP machine

  This study tests berobenatide versus placebo in adults with moderate-to-severe obstructive sleep apnea and overweight or obesity who are not using PAP therapy.

  Recruiting at 3 sites Phase 3 Pfizer · Cullman, Alabama and 3 other locations · NCT07881757

• Berobenatide: how it enters the blood after different delivery methods in adults with overweight or obesity

  This study tests a single dose of Berobenatide to see how it behaves in the body when given in different delivery forms to adults with overweight or obesity.

  Recruiting Phase 1 Pfizer · Anaheim, California · NCT07876531

• Switching to a monthly dose of Berobenatide to help keep weight off after weight loss with semaglutide or tirzepatide

  This study tests whether switching to a monthly berobenatide shot can help adults who have overweight or obesity and have already lost weight using semaglutide or tirzepatide to keep the weight off.

  Recruiting at 18 sites Phase 3 Pfizer · Birmingham, Alabama and 25 other locations · NCT07845500

• Berobenatide in adults with sleep apnea and obesity using a PAP machine

  This study tests berobenatide vs. placebo in adults with moderate to severe obstructive sleep apnea and overweight/obesity who use a PAP device.

  Recruiting at 6 sites Phase 3 Pfizer · Cullman, Alabama and 7 other locations · NCT07823608

• Body- or Mind-based regulation in women with overweight or obesity

  This study tests whether a body-based regulation program or a mind-based regulation program helps women with overweight or obesity improve heart rate regulation and emotional eating.

  Recruiting Pamukkale University · Denizli · NCT07738263

• Semaglutide delivered by a needle-free skin patch versus injections in adults with overweight or obesity

  This early study tests a needle-free skin patch delivering semaglutide against standard injections in adults who are overweight or obese to see if the patch works safely and as well as injections.

  Recruiting Phase 1 Terrestrial Bio, Inc. · Tempe, Arizona · NCT07673900

• Berobenatide (PF-08653944) for overweight or obesity in adults

  This study tests whether berobenatide helps adults with overweight or obesity lose weight compared with a placebo.

  Recruiting at 75 sites Phase 3 Pfizer · Canoga Park, California and 79 other locations · NCT07595549

• Brief Inhibitory Control Training for Overweight Teens

  Teens aged 14–17 with overweight or obesity will try three weeks of daily brain games on a smartphone to see if it helps with self-control around food and eating for better diet choices.

  Recruiting George Mason University · Fairfax, Virginia · NCT07592728

• Whole-body high-intensity interval training to improve fitness and body composition in adults with overweight

  This 10-week supervised program tests whether whole-body high-intensity interval training can improve fitness, strength, and body composition in adults aged 18–55 with a BMI of 25–35.

  Recruiting Université Libre de Bruxelles · Brussels · NCT07582718

• Six-month high-fiber, high-polyphenol diet to lower brain inflammation in perimenopausal women with overweight or obesity

  This will try a 6-month high-fiber, high-polyphenol (polybiotic) diet to see if it lowers brain inflammation in perimenopausal women with overweight or obesity.

  Recruiting Max Planck Institute for Human Cognitive and Brain Sciences · Leipzig, Saxony · NCT07501377

• Oral ecnoglutide tablets for weight management in Chinese adults with overweight or obesity

  This trial will test whether daily or weekly oral ecnoglutide tablets help Chinese adults with overweight or obesity and are safe and well tolerated.

  Recruiting Phase 1/2 Hangzhou Sciwind Biosciences Co., Ltd. · Beijing, Beijing Municipality · NCT07243171

• ERCG (clip-and-loop endoscopic gastric reduction) versus optimized lifestyle for weight loss

  This trial will test whether ERCG, a sutureless endoscopic clip-and-loop procedure that reduces stomach volume, helps Chinese adults with BMI 24.0–37.4 kg/m² lose more weight than an optimized lifestyle program.

  Recruiting Beijing 302 Hospital · Beijing, Beijing Municipality and 1 other locations · NCT07237750

• Family nutrition program to prevent overweight and obesity in school-age children

  This project tests a family-focused mobile app plus a multidisciplinary program to help children ages 5–9 keep healthy eating habits and avoid excess weight.

  Recruiting Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran · México, Sonora · NCT07159971

• Improving heart health in Norwegians with severe mental illness

  This trial will test whether a 6‑month program of dietary counseling and regular exercise can lower estimated heart disease risk in adults with schizophrenia-spectrum or bipolar I disorder who are overweight and on antipsychotic medication or lithium.

  Recruiting University of Oslo · Oslo · NCT07085923

• Doravirine/TDF/3TC versus Bictegravir/FTC/TAF for adults with HIV who are overweight or obese

  This trial will test whether a doravirine-based HIV pill or a bictegravir-based HIV pill leads to less weight gain in adults with HIV who are overweight or obese starting antiretroviral therapy.

  Recruiting Phase 3 Instituto Mexicano del Seguro Social · Mexico City · NCT07075146

Related topics

Quick answers

How many Overweight and/or Obesity clinical trials are recruiting right now?

16, as of November 12, 2026. 3 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 16 countries. The most sites are in United States (8 trials), Mexico (3 trials), Germany (2 trials), China (2 trials), Brazil (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 6, Phase 1: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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