Whole-body high-intensity interval training to improve fitness and body composition in adults with overweight

Effects of a Whole-body High-intensity Interval Training on Cardiorespiratory Fitness, Musculoskeletal Fitness, Body Composition and Blood Parameters in Overweight Subjects

NA · Université Libre de Bruxelles · NCT07582718

This 10-week supervised program tests whether whole-body high-intensity interval training can improve fitness, strength, and body composition in adults aged 18–55 with a BMI of 25–35.

Quick facts

PhaseNA
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years to 55 Years
SexAll
SponsorUniversité Libre de Bruxelles (other)
Locations1 site (Brussels)
Trial IDNCT07582718 on ClinicalTrials.gov

What this trial studies

This in-person study enrolls 40 adults with BMI 25–35 who are allocated to either a supervised whole-body HIIT program or a control group. The intervention consists of 2–3 supervised, small-group sessions per week for 10 weeks using 8–12 body-weight exercises performed at high intensity with short recovery intervals and progression guided by heart rate and perceived exertion. Participants complete comprehensive pre- and post-intervention testing including DXA body composition, fasting blood tests, muscular strength measures, a Chester step test, a maximal graded treadmill test with gas exchange to determine VO2peak, and functional evaluations. All training and assessments are conducted on site under exercise-professional supervision.

Who should consider this trial

Good fit: Adults aged 18–55 with BMI between 25 and 35 kg/m² who can safely perform high-intensity exercise and, if BMI > 30, can obtain medical clearance from their general practitioner.

Not a fit: Individuals with BMI outside 25–35, pregnant people, or those with chronic cardiovascular, metabolic, respiratory, or musculoskeletal conditions or other contraindications to high-intensity exercise are unlikely to benefit or be eligible.

Why it matters

Potential benefit: If successful, this program could offer a time-efficient, equipment-free way to improve cardiorespiratory fitness, muscular strength, and body composition for adults with excess weight.

How similar studies have performed: Prior HIIT trials in people with overweight or obesity have often improved VO2peak, strength, and body composition, although whole-body, equipment-free WB-HIIT has been less extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 18 to 55 years.
* Body mass index (BMI) between 25 and 35 kg/m².
* Able to provide written informed consent.
* Able to safely participate in high-intensity interval training.
* For participants with BMI \> 30 kg/m²: medical clearance from their general practitioner.

Exclusion Criteria:

* BMI \< 25 or \> 35 kg/m².
* Presence of any chronic medical condition other than overweight/obesity.
* Known cardiovascular, metabolic, respiratory, or musculoskeletal disease that contraindicates high-intensity exercise.
* Pregnancy.
* Inability to perform exercise testing or complete the WB-HIIT program.
* Any condition judged by investigators to interfere with participation or data interpretation.

Where this trial is running

Brussels

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Overweight and/or Obesity, Overweight, Cardiorespiratory Fitness, Body Composition, Muscular Strength, Whole-Body HIIT, Body-Weight Exercise, Metabolic health

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.