Condition
Overactive Bladder (OAB) clinical trials and research
As of November 12, 2026, Find a Trial lists 19 Overactive Bladder (OAB) clinical trials that are recruiting, at sites in 9 countries (most in United States (9), Turkey (Türkiye) (3), Australia (2)). By phase: Phase 4 (3), Phase 2 (2). The most active sponsors are Axonics, Inc. (2), Mansoura University (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 19Clinical trials
- 9Countries
Newest Overactive Bladder (OAB) clinical trials
All recruiting trials (19)
-
Predictive value of inflammatory biomarkers for mirabegron response in women with overactive bladder
This study tests whether baseline blood inflammation markers can predict how well women with OAB respond to mirabegron after 3 months.
-
NT 201 therapy delivered via the Vibe System for idiopathic overactive bladder
This Phase 2b trial tests NT 201 given with the Vibe System to see if it helps adults with idiopathic overactive bladder compared to placebo or sham treatment.
-
Ambulatory tibial nerve stimulation for overactive bladder in adults
A portable nerve-stimulation device used at home is being tested to see if it can reduce urgency and improve bladder symptoms in adults with overactive bladder.
-
Low-intensity shockwave versus daily solifenacin for women's overactive bladder
This test compares once-weekly low-intensity shockwave therapy with daily solifenacin to see which better reduces overactive bladder symptoms in adult women.
-
Low-dose tadalafil versus solifenacin for treating overactive bladder in women
This trial will test whether taking daily low-dose tadalafil or daily solifenacin reduces overactive bladder symptoms in women aged 18–75.
-
Zinc plus phytase given before botulinum toxin injections for overactive bladder
This trial will test whether a short course of oral zinc plus phytase before botulinum toxin bladder injections helps adult women with overactive bladder go longer without needing another injection over six months.
-
Aquarius Pilot of the New Axonics External System for Bladder and Bowel Control
This pilot will try the Axonics External Trial System in adults with overactive bladder or fecal incontinence to see if they respond to sacral neuromodulation before getting a permanent implant.
-
Tensi+ device for overactive bladder using Transcutaneous Tibial Nerve Stimulation
A device called Tensi+ is being tested to see if it is safe and helps reduce OAB symptoms like urgent need to go and frequency in adults.
-
Vaginal radiofrequency treatment targeting bladder nerves for overactive bladder in women
This trial will test whether a single vaginal radiofrequency treatment with the MORPHEUSV device can reduce urgency-related urine leaks in adult women with overactive bladder.
-
FemPulse non-implanted electrical stimulation for overactive bladder.
This trial will test whether the FemPulse external electrical stimulation device can reduce overactive bladder symptoms in adult women.
-
Personalised sacral neuromodulation (INO-SNM-01) for overactive bladder
This will test whether a personalised sacral neuromodulation device (INO-SNM-01) can detect bladder nerve signals and deliver targeted stimulation to reduce symptoms in adult women whose overactive bladder has not responded to standard treatments.
-
Home-based remote posterior tibial nerve stimulation for overactive bladder
This trial tests whether a home-based, app-controlled posterior tibial nerve stimulation device can reduce symptoms in adults with overactive bladder.
-
Oxybutynin versus posterior tibial nerve stimulation for children with idiopathic overactive bladder
This trial will test whether weekly posterior tibial nerve stimulation works as well as daily oxybutynin for treating idiopathic overactive bladder in children aged 6–16.
-
Mirabegron, solifenacin, combined therapy, and Botox for women with overactive bladder in Taiwan
This will test whether mirabegron, solifenacin, their combination, or intradetrusor Botox reduce the bladder's mechanical work and change bladder compliance in women with overactive bladder.
-
Genitourinary microbiome before and after Botox bladder injections in postmenopausal women
We're trying to see if the bacteria in the urine change in postmenopausal women with overactive bladder before and four weeks after Botox bladder injections.
-
Methenamine Hippurate After BOTOX-A Injections for Overactive Bladder
This study tests whether methenamine hippurate can prevent urinary infections after BOTOX-A injections in women with overactive bladder, compared with standard antibiotic prophylaxis.
-
Axonics rechargeable sacral neuromodulation system (Model 5101 R20) for overactive bladder
This study will test whether the rechargeable Axonics sacral neuromodulation system (Model 5101 R20) stays safe and continues to control symptoms over time in adults with overactive bladder, including urgency incontinence and frequent urination.
-
Combining neuromodulation and exercise for treating urinary incontinence
This study is testing if combining special exercises with nerve stimulation can help menopausal women with urge urinary incontinence and overactive bladder feel better.
-
Cefar URO: a home TTNS test for adults with overactive bladder
This study tests at-home transcutaneous tibial nerve stimulation with the Cefar URO device to see if it helps adults with overactive bladder symptoms.
Related topics
Quick answers
How many Overactive Bladder (OAB) clinical trials are recruiting right now?
19, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 9 countries. The most sites are in United States (9 trials), Turkey (Türkiye) (3 trials), Australia (2 trials), France (2 trials), Egypt (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 3, Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.