Combining neuromodulation and exercise for treating urinary incontinence
Official title: Effect of a Peripheral and Central Neuromodulation Protocol Combined With the Application of Therapeutic Exercise in Patients Diagnosed With Urinary Incontinence. A Randomized Control Trial (RCT)
Run by Fundación Universidad Católica de Valencia San Vicente Mártir · NCT06783374 · Data updated 2026-11-12
This study is testing if combining special exercises with nerve stimulation can help menopausal women with urge urinary incontinence and overactive bladder feel better.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 45 Years and up |
| Sex | Women only |
| Enrollment | 63 (estimated) |
| Sponsor | Fundación Universidad Católica de Valencia San Vicente Mártir Academic / other |
| Locations | 1 site (Valencia, Valencia) |
| Status | Recruiting |
| Started | March 4, 2025 |
| Main results expected | November 10, 2026 |
| Study ends | November 10, 2026 |
| Registry record updated | April 13, 2025 |
| Trial ID | NCT06783374 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are women over 45 years old who have been diagnosed with urinary incontinence or overactive bladder for at least three months.
✕Probably not a fit
Patients with stress urinary incontinence or those with neurological or psychiatric disorders may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of combining therapeutic exercise with neuromodulation techniques to treat urge urinary incontinence (UUI) and overactive bladder (OAB) in menopausal women. The approach focuses on modulating the neurophysiology of bladder functionality through pelvic floor strength training and peripheral neuromodulation. Participants will be assessed for their response to these interventions over a specified duration, with a control group receiving sham neuromodulation. The goal is to improve quality of life by reducing the symptoms associated with UUI.
Why it matters
Potential benefit: If successful, this approach could significantly improve the management of urinary incontinence and enhance the quality of life for affected patients.
How similar studies have gone: While the combination of neuromodulation and exercise is a novel approach, similar studies have shown promise in treating overactive bladder symptoms.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Present with a diagnosis of urinary incontinence or overactive bladder * Women of menopausal age (\>45 years) * ≥3 months of duration * Fulfill the established criteria for patient selection for neuromodulation treatment (urge urinary incontinence) * Speak native Spanish or English Exclusion Criteria: * Prior or scheduled surgical procedures in the lumbar or abdominal region * Presence of fractures or severe pathological conditions * Current pregnancy or potential for pregnancy during the study period * Neurological or psychiatric disorders * Presence of stress urinary incontinence * Female subjects with autoimmune diseases or malignancies * Belonephobia * Subjects who have undergone previous neuromodulation
Where it's running
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Catholic Univerity of Valencia
Valencia, Valencia, Spain Recruiting
Study contacts
- Study coordinator: Jesica L-G Leal García, PhD Student
- Email: jesica.leal@ucv.es
- Phone: +34 657390304
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Vaginal radiofrequency treatment targeting bladder nerves for overactive bladder in women
This trial will test whether a single vaginal radiofrequency treatment with the MORPHEUSV device can reduce urgency-related urine leaks in adult women with overactive bladder.
-
Predictive value of inflammatory biomarkers for mirabegron response in women with overactive bladder
This study tests whether baseline blood inflammation markers can predict how well women with OAB respond to mirabegron after 3 months.
-
NT 201 therapy delivered via the Vibe System for idiopathic overactive bladder
This Phase 2b trial tests NT 201 given with the Vibe System to see if it helps adults with idiopathic overactive bladder compared to placebo or sham treatment.
-
Ambulatory tibial nerve stimulation for overactive bladder in adults
A portable nerve-stimulation device used at home is being tested to see if it can reduce urgency and improve bladder symptoms in adults with overactive bladder.
-
Low-intensity shockwave versus daily solifenacin for women's overactive bladder
This test compares once-weekly low-intensity shockwave therapy with daily solifenacin to see which better reduces overactive bladder symptoms in adult women.
-
Long-term safety and durability of the Altaviva tibial device for urge urinary incontinence
It will test whether the Altaviva tibial nerve system safely reduces urge urinary incontinence in adults who meet the device's candidate criteria.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.