Ambulatory tibial nerve stimulation for overactive bladder in adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, randomized study compares two ways of delivering tibial nerve stimulation for overactive bladder. One group receives traditional clinic-based TTNS sessions, while the other uses a portable device at home during daily activities over a four-week period. Both groups use identical electrical settings (20 Hz, 200 µs) and complete symptom questionnaires before and after the treatment window. The trial is conducted at Başakşehir Çam and Sakura City Hospital in Istanbul and aims to determine if ambulatory TTNS is as effective as clinic-based TTNS in reducing urgency episodes and improving quality of life.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 to 65 years
* Clinical diagnosis of overactive bladder (OAB)
* Working in an office setting or spending most of the day at home, suitable for using a portable TENS device

Exclusion Criteria:

* Pregnancy
* Cardiac pacemaker
* Epilepsy
* Metal implant in the ankle area
* Open wound or skin disease at the electrode site
* Active urinary tract infection
* Neurological disease affecting bladder function
* Previous surgery for urinary incontinence or OAB
* Current anticholinergic or beta-3 agonist use for OAB
* Cognitive impairment preventing proper device use

Where it's running

• Başakşehir Çam and Sakura City Hospital, Department of Urology
  Istanbul, Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Veysel Sezgin Sezgin, M.D
• Email: veyselsezgin1@gmail.com
• Phone: +905513895655

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Predictive value of inflammatory biomarkers for mirabegron response in women with overactive bladder

  This study tests whether baseline blood inflammation markers can predict how well women with OAB respond to mirabegron after 3 months.

  Recruiting Bagcilar Training and Research Hospital · Istanbul, Bagcilar · NCT07773532

• NT 201 therapy delivered via the Vibe System for idiopathic overactive bladder

  This Phase 2b trial tests NT 201 given with the Vibe System to see if it helps adults with idiopathic overactive bladder compared to placebo or sham treatment.

  Recruiting at 3 sites Phase 2 Vensica Therapeutics Ltd. · Margate, Florida and 2 other locations · NCT07553065

• Low-intensity shockwave versus daily solifenacin for women's overactive bladder

  This test compares once-weekly low-intensity shockwave therapy with daily solifenacin to see which better reduces overactive bladder symptoms in adult women.

  Recruiting Phase 4 Mansoura University · Al Mansurah, Dakahlia Governorate · NCT07473310

• Low-dose tadalafil versus solifenacin for treating overactive bladder in women

  This trial will test whether taking daily low-dose tadalafil or daily solifenacin reduces overactive bladder symptoms in women aged 18–75.

  Recruiting at 14 sites Phase 4 Mansoura University · Shibīn al Kawm, Al-Minūfiyyah and 13 other locations · NCT07416968

• Zinc plus phytase given before botulinum toxin injections for overactive bladder

  This trial will test whether a short course of oral zinc plus phytase before botulinum toxin bladder injections helps adult women with overactive bladder go longer without needing another injection over six months.

  Recruiting Phase 2 Endeavor Health · Skokie, Illinois · NCT07405554

• Aquarius Pilot of the New Axonics External System for Bladder and Bowel Control

  This pilot will try the Axonics External Trial System in adults with overactive bladder or fecal incontinence to see if they respond to sacral neuromodulation before getting a permanent implant.

  Recruiting at 5 sites Axonics, Inc. · Birmingham, Alabama and 4 other locations · NCT07335484

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.