FemPulse non-implanted electrical stimulation for overactive bladder.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares a non-implanted FemPulse electrical stimulation device to standard medication management in adult women with overactive bladder. Participants are enrolled at multiple Southern California centers and must have physician-confirmed OAB symptoms for more than six months and be able to comply with study procedures. Study procedures include assignment to a device or medication group, scheduled clinic visits, symptom diaries, and safety monitoring. Primary outcomes focus on device safety and changes in urgency, frequency, nocturia, and incontinence over the treatment period.

Why it matters

Who can join: the full rules

Key Inclusion Criteria:

* Females, defined as a person with a uterus and cervix, ≥21 years old, with a diagnosis of OAB and symptoms for more than 6 months, as confirmed by a physician. OAB is defined by urinary urgency, usually with urinary frequency and nocturia, with or without urgency urinary incontinence with symptoms
* Willing and able to comply with study required procedures and visits (e.g., maintaining consistent medication use, fluid intake, diary completion).

Key Exclusion Criteria:

* Systemic condition or disease that may interfere with study participation (e.g., current systemic infection, uncontrolled autoimmune disease, uncontrolled immunodeficiency disease, history of myocardial infarction, etc.) as determined by study investigator.
* Not an appropriate study candidate as determined by investigator.

Where it's running

• Cedars Sinai
  Beverly Hills, California, United States Recruiting
• UCLA
  Los Angeles, California, United States Recruiting
• UC Irvine
  Orange, California, United States Recruiting
• Stanford
  Palo Alto, California, United States Recruiting
• Uscd
  San Diego, California, United States Recruiting
• Holy Cross Medical Group - Women's Center
  Fort Lauderdale, Florida, United States Recruiting

Study contacts

• Principal investigator: Suzette Sutherland, MD — FemPulse Corporation
• Study coordinator: Monica Unger
• Email: monica.unger@moxieclinical.com
• Phone: 7275123718

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Predictive value of inflammatory biomarkers for mirabegron response in women with overactive bladder

  This study tests whether baseline blood inflammation markers can predict how well women with OAB respond to mirabegron after 3 months.

  Recruiting Bagcilar Training and Research Hospital · Istanbul, Bagcilar · NCT07773532

• NT 201 therapy delivered via the Vibe System for idiopathic overactive bladder

  This Phase 2b trial tests NT 201 given with the Vibe System to see if it helps adults with idiopathic overactive bladder compared to placebo or sham treatment.

  Recruiting at 3 sites Phase 2 Vensica Therapeutics Ltd. · Margate, Florida and 2 other locations · NCT07553065

• Ambulatory tibial nerve stimulation for overactive bladder in adults

  A portable nerve-stimulation device used at home is being tested to see if it can reduce urgency and improve bladder symptoms in adults with overactive bladder.

  Recruiting Başakşehir Çam & Sakura City Hospital · Istanbul, Istanbul · NCT07540273

• Low-intensity shockwave versus daily solifenacin for women's overactive bladder

  This test compares once-weekly low-intensity shockwave therapy with daily solifenacin to see which better reduces overactive bladder symptoms in adult women.

  Recruiting Phase 4 Mansoura University · Al Mansurah, Dakahlia Governorate · NCT07473310

• Low-dose tadalafil versus solifenacin for treating overactive bladder in women

  This trial will test whether taking daily low-dose tadalafil or daily solifenacin reduces overactive bladder symptoms in women aged 18–75.

  Recruiting at 14 sites Phase 4 Mansoura University · Shibīn al Kawm, Al-Minūfiyyah and 13 other locations · NCT07416968

• Zinc plus phytase given before botulinum toxin injections for overactive bladder

  This trial will test whether a short course of oral zinc plus phytase before botulinum toxin bladder injections helps adult women with overactive bladder go longer without needing another injection over six months.

  Recruiting Phase 2 Endeavor Health · Skokie, Illinois · NCT07405554

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.