Condition

Osteoarthritis of the Knee clinical trials and research

• 7Clinical trials
• 1New in 30 days
• 6Countries

Newest Osteoarthritis of the Knee clinical trials

All recruiting trials (7)

• Berobenatide for knee pain in adults who are overweight or with obesity

  This study tests berobenatide vs. placebo to see if it reduces knee pain and improves function while helping with weight in adults with knee osteoarthritis and overweight/obesity.

  Recruiting at 7 sites Phase 3 Pfizer · Tempe, Arizona and 39 other locations · NCT07919678

• Single intra-articular injection of celecoxib (AVD275) to check safety and drug levels in knee osteoarthritis.

  This will test a single injection of celecoxib (AVD275) at three different doses in adults with knee osteoarthritis to see if it is safe and how the drug stays in the joint.

  Recruiting Phase 1 Avidence Therapeutics · Wahroonga, New South Wales · NCT07338266

• Aerobic cycling versus therapeutic exercise for knee osteoarthritis pain sensitivity

  This trial tests whether aerobic cycling or a therapeutic exercise program better reduces exercise-related pain sensitivity in people aged 45–75 with knee osteoarthritis.

  Recruiting University of Nove de Julho · São Paulo and 1 other locations · NCT07302204

• Evaluating a new treatment for knee osteoarthritis using chondrocyte sheets

  This study is testing if a new treatment using chondrocyte sheets can help people with knee osteoarthritis feel better after surgery compared to those who only have the surgery.

  Recruiting at 6 sites Phase 3 CellSeed Inc. · Ebina, Kanagawa and 5 other locations · NCT06549686

• Comparing robotic-assisted and conventional knee replacement techniques

  This study is testing if robotic-assisted knee replacement surgery helps adults recover better and have fewer problems compared to traditional knee replacement surgery.

  Recruiting at 2 sites Danderyd Hospital · Hässleholm and 1 other locations · NCT06389435

• Comparing Bone Marrow Aspirate Concentrate to Corticosteroid Injections for Knee Osteoarthritis

  This study is testing whether injections of bone marrow concentrate can help people with knee osteoarthritis feel better compared to traditional corticosteroid injections.

  Recruiting Rush University Medical Center · Chicago, Illinois · NCT05985785

• Effects of cannabinoids on knee osteoarthritis pain

  This study is testing if daily treatment with THC, CBD, or both can help people with knee osteoarthritis feel less pain and improve their symptoms.

  Recruiting Phase 2 University of Michigan · Ann Arbor, Michigan · NCT04992624

Related topics

Quick answers

How many Osteoarthritis of the Knee clinical trials are recruiting right now?

7, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (3 trials), Sweden (1 trial), Australia (1 trial), Canada (1 trial), Brazil (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 1: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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