Condition

Opioid Use Disorder (OUD) clinical trials and research

• 8Clinical trials
• 2Countries

Newest Opioid Use Disorder (OUD) clinical trials

All recruiting trials (8)

• Mindfulness Text Messages to Support Medication Adherence and Pain Management

  This study tests whether daily reminder and mindfulness text messages can help people on medications for opioid use disorder with chronic pain stick to their treatment and better manage cravings and pain.

  Recruiting University of New Mexico · Albuquerque, New Mexico · NCT07711795

• Text reminders and mindfulness messages to support people taking opioid medications

  This project will test whether daily medication reminder texts plus up to six mindfulness messages per day help people taking medications for opioid use disorder stick to their medication and manage cravings, pain, and withdrawal.

  Recruiting University of New Mexico · Albuquerque, New Mexico · NCT07350148

• How ibogaine changes brain activity in opioid use disorder.

  This study will test whether ibogaine changes brain activity and symptoms in adults with moderate-to-severe opioid use disorder who are already planning legal treatment.

  Recruiting University of California, Irvine · Irvine, California · NCT07226570

• Personalized adaptive deep brain stimulation for severe opioid use disorder

  This study will test whether personalized deep brain stimulation guided by invasive brain mapping is safe and can reduce cravings and opioid use in adults with severe, treatment-resistant opioid use disorder.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07214467

• Autonomous nurse-led methadone delivery

  This test sees if allowing nurses to manage and give methadone helps people starting treatment for opioid use disorder.

  Recruiting at 4 sites Hospices Civils de Lyon · Bayonne and 7 other locations · NCT07085377

• Sparrow Link device to help with opioid withdrawal in hospitalized adults with OUD

  A wearable nerve-stimulation device is being tested to see if it can help reduce withdrawal symptoms in adults with opioid use disorder who are hospitalized and receiving standard care.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT07079826

• Cannabidiol added to methadone or buprenorphine for opioid recovery

  This trial will test whether adding cannabidiol (CBD) to methadone or buprenorphine helps people with opioid use disorder reduce craving and stop using illicit opioids.

  Recruiting at 2 sites Phase 3 Icahn School of Medicine at Mount Sinai · New York, New York and 1 other locations · NCT06940674

• Finding the right methadone loading dose for people with fentanyl opioid use disorder

  This trial tests whether giving a higher 'loading' methadone dose in a monitored setting helps adults with fentanyl opioid use disorder start methadone more safely and comfortably than standard dosing.

  Recruiting Phase 1 University of Pennsylvania · Philadelphia, Pennsylvania · NCT06877858

Related topics

Quick answers

How many Opioid Use Disorder (OUD) clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (7 trials), France (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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