Condition

NMIBC clinical trials and research

• 11Clinical trials
• 3NIH research projects
• 1New in 30 days
• 4Countries

Newest NMIBC clinical trials

All recruiting trials (11)

• 1-Year Recurrence After En Bloc Resection for Large Bladder Tumors

  This trial tests whether en bloc resection of bladder tumors larger than 2.5 cm can reduce recurrence compared with standard transurethral resection in adults with non-muscle invasive bladder cancer.

  Recruiting Phase 3 Rabin Medical Center · Petah Tikva · NCT07898033

• Feasibility of automatic, laser-based distance control in people with superficial bladder tumors

  This study tests whether the ATLAS system’s distance sensor can accurately guide laser treatment for Ta low-grade bladder tumors in patients during a scheduled outpatient procedure.

  Recruiting Optheras AS · Herlev · NCT07860398

• NMIBC sample collection to test cancer monitoring biomarkers

  This study tests a blood, urine, and tumor tissue collection approach in people with high-risk non-muscle invasive bladder cancer to see if a molecular test can detect residual disease and monitor recurrence.

  Recruiting Natera, Inc. · Austin, Texas · NCT07763197

• Intravesical UGN-501 for Recurrent NMIBC (Phase 1, dose-escalation)

  This study tests whether UGN-501 can be safely given into the bladder to treat adults with recurrent non-muscle invasive bladder cancer.

  Recruiting at 6 sites Phase 1 UroGen Pharma Ltd. · Queen Creek, Arizona and 14 other locations · NCT07725796

• Shr-1501 plus BCG vs physician-chosen chemotherapy for BCG-unresponsive non-muscle invasive bladder cancer

  This study tests whether SHR-1501 given with BCG works better than the doctor-selected chemotherapy for people with BCG-unresponsive non-muscle invasive bladder cancer.

  Recruiting at 2 sites Phase 3 Suzhou Suncadia Biopharmaceuticals Co., Ltd. · Beijing, Beijing Municipality and 1 other locations · NCT07424287

• Disitamab Vedotin plus BCG vs BCG alone in HER2-expressing high-risk NMIBC

  This study tests whether adding disitamab vedotin to BCG helps people with early, high-risk bladder cancer that hasn’t spread outside the bladder.

  Recruiting Phase 3 Fudan University · Shanghai, Shanghai Municipality · NCT07207824

• Monitoring recurrence of urothelial carcinoma using urinary tests

  This study is testing if urine tests can help track the return of urothelial carcinoma in patients with different types of bladder and kidney cancer.

  Recruiting Peking University First Hospital · Beijing, Beijing Municipality · NCT06991868

• Immediate chemotherapy after bladder tumor removal for high-risk patients

  This study tests if giving immediate chemotherapy after bladder tumor removal can help high-risk patients avoid cancer recurrence.

  Recruiting Changhai Hospital · Shanghai, Shanghai Municipality · NCT06889623

• Intravesical recombinant BCG for non‑muscle invasive bladder cancer

  This trial tests a recombinant form of BCG given directly into the bladder to see if it is safe and helps prevent recurrence in adults with BCG‑naïve NMIBC (CIS or Ta/T1).

  Recruiting at 5 sites Phase 1/2 ImmunityBio, Inc. · Chandler, Arizona and 8 other locations · NCT06800963

• Bladder-sparing treatment for large non-muscle-invasive bladder cancer

  This study is testing new bladder-sparing treatments for people with large non-muscle-invasive bladder cancer to see if they can improve outcomes while keeping the bladder intact.

  Recruiting The First Affiliated Hospital with Nanjing Medical University · Nanjing, Jiangsu · NCT06735287

• Treatment for high-risk non-muscle-invasive bladder cancer

  This study is testing a new treatment combining RC48-ADC and gemcitabine for people with high-risk non-muscle-invasive bladder cancer who haven't had BCG treatment or didn't respond to it.

  Recruiting Phase 2 RemeGen Co., Ltd. · Beijing, Beijing Municipality · NCT05943379

NIH-funded research (3)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Calm Bladder: Acupuncture to ease urinary symptoms during NMIBC treatment

  A multicenter trial will test whether weekly acupuncture before bladder cancer therapy helps reduce urinary symptoms and improve quality of life for adults with non-muscle-invasive bladder cancer.

  NIH research University of Washington · Seattle, United States · NIH-11339979

• Improving treatment choices for recurrent bladder cancer

  This project helps patients with recurrent bladder cancer and their doctors make better decisions about whether to remove the bladder or try other treatments.

  NIH research University of Washington · Seattle, United States · NIH-11082335

• Comparing bladder-sparing therapies and surgery for recurrent bladder cancer

  This study is looking at different treatment options for people with recurring non-muscle invasive bladder cancer to help them and their doctors make better choices about whether to try bladder-sparing therapies or go for surgery, all with the goal of improving their health and quality of life.

  NIH research University of Washington · Seattle, United States · NIH-10856797

Related topics

Quick answers

How many NMIBC clinical trials are recruiting right now?

11, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in China (6 trials), United States (3 trials), Denmark (1 trial), Israel (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 3, Phase 2: 1, Phase 1: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →