Condition

Bladder (Urothelial, Transitional Cell) Cancer clinical trials and research

• 15Clinical trials
• 1New in 30 days
• 7Countries

Newest Bladder (Urothelial, Transitional Cell) Cancer clinical trials

All recruiting trials (15)

• BL-M07D1: T-bren vs standard platinum chemo for HER2-expressing metastatic urothelial cancer after anti-PD-(L)1 therapy

  This trial tests whether T-bren can help people with HER2-expressing metastatic urothelial cancer who progressed after anti-PD-(L)1 therapy, compared with standard platinum-based chemotherapy.

  Recruiting at 2 sites Phase 3 SystImmune Inc. · Macon, Georgia and 1 other locations · NCT07869836

• Intravesical UGN-501 for Recurrent NMIBC (Phase 1, dose-escalation)

  This study tests whether UGN-501 can be safely given into the bladder to treat adults with recurrent non-muscle invasive bladder cancer.

  Recruiting at 6 sites Phase 1 UroGen Pharma Ltd. · Queen Creek, Arizona and 14 other locations · NCT07725796

• Is ongoing systemic immunotherapy needed after achieving tumor-free status in very-high-risk NMIBC?

  This study tests whether patients who have become tumor-free after a systemic immunotherapy-based bladder-sparing treatment can safely stop therapy and instead be watched closely.

  Recruiting at 4 sites Phase 2 Tianjin Medical University Second Hospital · Tianjin and 3 other locations · NCT07625527

• Irrigation Fluid Absorption and Perioperative cfDNA Changes in TURBT for Bladder Cancer

  This study tests whether the amount of irrigation fluid absorbed during TURBT is linked to changes in tumor DNA circulating in the blood in patients with bladder cancer.

  Recruiting Lanzhou University Second Hospital · Lanzhou, Gansu · NCT07589413

• TARA-002 vs chemotherapy for high-grade non-muscle invasive bladder cancer in adults not previously treated with BCG

  A phase 3 study tests whether TARA-002 can help adults with high-grade non-muscle invasive bladder cancer who haven’t had BCG, comparing it to standard intravesical chemotherapy.

  Recruiting at 11 sites Phase 3 Protara Therapeutics · Queen Creek, Arizona and 10 other locations · NCT07480356

• Liquid biopsy testing to identify, monitor, and predict recurrence in urothelial carcinoma

  This project tests whether a multi-component liquid biopsy (blood and urine ctDNA, urine tumor DNA, exosomes, and protein biomarkers) can help detect disease, track treatment response, and predict recurrence in people with suspected or confirmed urothelial carcinoma.

  Recruiting Tianjin Medical University Second Hospital · Tianjin · NCT07441499

• Disitamab Vedotin plus BCG vs BCG alone in HER2-expressing high-risk NMIBC

  This study tests whether adding disitamab vedotin to BCG helps people with early, high-risk bladder cancer that hasn’t spread outside the bladder.

  Recruiting Phase 3 Fudan University · Shanghai, Shanghai Municipality · NCT07207824

• Vitamin B3 to help immunotherapy work better in bladder cancer

  A early-phase study tests whether Vitamin B3 can help immunotherapy drugs work better for adults with bladder cancer.

  Recruiting Phase 1 Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT07119996

• Bladder cancer and urinary microbiota in adults

  This study looks to see if the bacteria in the bladder relate to bladder cancer in adults.

  Recruiting Centre Hospitalier Universitaire de Nice · Cannes and 7 other locations · NCT07080333

• Personalized 6-month program to reduce frailty around bladder or kidney cancer surgery

  This program will try personalized exercise, education workshops, and referral to a rehabilitation service before and after surgery to reduce frailty in older people having bladder or kidney cancer operations.

  Recruiting Centre Hospitalier Universitaire de Saint Etienne · Saint-Etienne and 1 other locations · NCT07073703

• MRI-first treatment pathway for muscle-invasive bladder cancer

  This trial tests whether using a multiparametric bladder MRI to skip a staging TURBt can speed up care for people with biopsy-proven muscle-invasive bladder cancer.

  Recruiting Phase 3 University of Rome Tor Vergata · Rome, RM · NCT07067749

• Virtual exercise program to preserve function and prevent disability during chemotherapy

  This trial tests whether supervised resistance sessions by video plus short home aerobic workouts help adults 18–64 maintain strength and stay active while receiving curative-intent chemotherapy.

  Recruiting at 29 sites Alliance for Clinical Trials in Oncology · Dublin, California and 29 other locations · NCT07059884

• Gemcitabine chemoablation for low-grade bladder cancer

  This study will try weekly bladder instillations of the chemotherapy drug gemcitabine to remove or control small, low-grade (Ta) bladder tumors in adults.

  Recruiting Phase 2 Medical University of Vienna · Vienna · NCT07019220

• Identifying Hypoxic Tumors for Improved Cancer Treatment

  This study is testing a way to find tumors with low oxygen levels in bladder and prostate cancer patients to see if personalizing their treatment can help them respond better to radiotherapy.

  Recruiting University of Manchester · Manchester · NCT06787053

• Combining Clostridium Butyricum with PD1 inhibitors for bladder cancer treatment

  This study is testing if adding Clostridium butyricum to PD1 inhibitors can help improve treatment results for bladder cancer patients.

  Recruiting Phase 2 The First Affiliated Hospital with Nanjing Medical University · Nanjing, Jiangsu · NCT06696742

Related topics

Quick answers

How many Bladder (Urothelial, Transitional Cell) Cancer clinical trials are recruiting right now?

15, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in China (6 trials), United States (4 trials), France (2 trials), Italy (1 trial), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 4, Phase 2: 3, Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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