Condition

Urothelial Carcinoma Bladder clinical trials and research

• 14Clinical trials
• 1New in 30 days
• 7Countries

Newest Urothelial Carcinoma Bladder clinical trials

All recruiting trials (14)

• BL-M07D1: T-bren vs standard platinum chemo for HER2-expressing metastatic urothelial cancer after anti-PD-(L)1 therapy

  This trial tests whether T-bren can help people with HER2-expressing metastatic urothelial cancer who progressed after anti-PD-(L)1 therapy, compared with standard platinum-based chemotherapy.

  Recruiting at 2 sites Phase 3 SystImmune Inc. · Macon, Georgia and 1 other locations · NCT07869836

• Intravesical UGN-501 for Recurrent NMIBC (Phase 1, dose-escalation)

  This study tests whether UGN-501 can be safely given into the bladder to treat adults with recurrent non-muscle invasive bladder cancer.

  Recruiting at 6 sites Phase 1 UroGen Pharma Ltd. · Queen Creek, Arizona and 14 other locations · NCT07725796

• Calcium electroporation for bladder tumors in adults who can’t have standard treatments

  This first‑in‑human study tests intravesical calcium electroporation to see if it is safe and whether it shows early signs of benefit in adults with bladder tumors who have few other options.

  Recruiting Phase 1 Zealand University Hospital · Roskilde · NCT07555769

• Nectin-4 targeted alpha radiotherapy [225Ac]Ac-AKY-1189 for advanced solid tumors

  This trial will try a Nectin‑4–targeted radioactive drug called [225Ac]Ac‑AKY‑1189 in adults with locally advanced or metastatic solid tumors, including certain bladder, breast, lung, and cervical cancers.

  Recruiting at 14 sites Phase 1 Aktis Oncology, Inc. · Duarte, California and 13 other locations · NCT07020117

• Combination treatment for advanced urothelial carcinoma

  This study is testing a new combination of a drug called AM80 with standard chemotherapy and immunotherapy to see if it helps people with advanced bladder cancer feel better and live longer.

  Recruiting Phase 2 Nagoya University · Nagoya, Aichi-ken · NCT06983210

• Comparing two treatments for advanced urothelial carcinoma

  This study is testing if a combination of two treatments can help people with advanced bladder cancer do better than using just one of the treatments alone.

  Recruiting at 2 sites Phase 2 Mabwell (Shanghai) Bioscience Co., Ltd. · Changsha, Hunan and 1 other locations · NCT06823427

• European validation of Bladder EpiCheck for haematuria

  This project will see if the Bladder EpiCheck urine methylation test can detect urothelial cancer in people aged 45 and older who have visible or non-visible blood in their urine.

  Recruiting at 5 sites Nucleix Ltd. · Dunfermline, Fife and 4 other locations · NCT06818136

• Impact of Preoperative Physical Activity on Bladder Cancer Surgery Outcomes

  This study is testing if being more physically active before bladder cancer surgery can help patients recover better and have fewer complications.

  Recruiting Ludwig-Maximilians - University of Munich · Munich, Bavaria · NCT06806059

• Combining immunotherapy and radiation for bladder cancer treatment

  This study is testing if giving immunotherapy and radiation together is safe for people with bladder cancer who have had surgery.

  Recruiting Phase 1 Abramson Cancer Center at Penn Medicine · Philadelphia, Pennsylvania · NCT06586255

• Treatment of advanced solid tumors with VET3-TGI immunotherapy

  This study is testing a new cancer treatment called VET3-TGI to see if it can safely target and kill cancer cells in patients with advanced solid tumors, either by injecting it directly into the tumors or giving it through an IV.

  Recruiting at 7 sites Phase 1 KaliVir Immunotherapeutics · Los Angeles, California and 6 other locations · NCT06444815

• Decision tool for selecting women for bladder surgery

  This study is testing a new decision-making tool to help doctors choose which women with bladder cancer can safely have surgery without losing their reproductive organs.

  Recruiting Phase 2 University of Florida · Gainesville, Florida · NCT06184516

• Combination therapy for high grade upper tract urothelial cancer patients refusing surgery

  This study is testing if a combination of two cancer drugs can help people with high grade upper tract urothelial cancer who don't want surgery live longer without their cancer getting worse.

  Recruiting at 2 sites Phase 2 Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Washington D.C., District of Columbia and 1 other locations · NCT05656235

• Combining Atezolizumab with Etoposide and Platinum for Small Cell Bladder Cancer

  This study is testing if a new combination of atezolizumab, etoposide, and platinum-based chemotherapy can help people with advanced small cell bladder cancer respond better to treatment before surgery.

  Recruiting at 2 sites Phase 2 Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Washington D.C., District of Columbia and 1 other locations · NCT05312671

• Evaluating Verity-BCG for treating high-risk non-muscle invasive bladder cancer

  This study is testing a new treatment called Verity-BCG to see if it can help people with high-risk bladder cancer stay cancer-free for longer compared to the standard treatment they usually receive.

  Recruiting at 4 sites Phase 3 Verity Pharmaceuticals Inc. · Vancouver, British Columbia and 5 other locations · NCT05037279

Related topics

Quick answers

How many Urothelial Carcinoma Bladder clinical trials are recruiting right now?

14, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (8 trials), China (1 trial), Japan (1 trial), Denmark (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 5, Phase 1: 5, Phase 3: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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