Condition
Motor Neuron Disease, Amyotrophic Lateral Sclerosis clinical trials and research
As of November 12, 2026, Find a Trial lists 4 Motor Neuron Disease, Amyotrophic Lateral Sclerosis clinical trials that are recruiting, at sites in 3 countries (most in United States (2), United Kingdom (1), Australia (1)). By phase: Phase 2/3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 3Countries
Newest Motor Neuron Disease, Amyotrophic Lateral Sclerosis clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Electrical stimulation to reduce facial pain and improve jaw movement and chewing in people with motor neuron disease | — | Davie, Florida | Recruiting | Sep 23, 2025 |
| Observational study on amyotrophic lateral sclerosis | — | Watertown, Massachusetts | Recruiting | Mar 20, 2025 |
| Using sleep studies to improve breathing support in motor neurone disease | — | Adelaide and 12 other locations | Recruiting | Nov 29, 2021 |
| Testing drugs to slow down motor neurone disease progression | Phase 2/3 | Portadown, County Armagh and 21 other locations | Recruiting | Mar 10, 2020 |
All recruiting trials (4)
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Electrical stimulation to reduce facial pain and improve jaw movement and chewing in people with motor neuron disease
This trial will try one 30-minute session of non-invasive facial electrical stimulation to see if it reduces jaw and facial pain and improves chewing and jaw movement for people with ALS or PLS.
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Observational study on amyotrophic lateral sclerosis
This study is collecting health information from people with ALS, those with related genetic mutations, and healthy volunteers to help improve treatments and understand the disease better.
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Using sleep studies to improve breathing support in motor neurone disease
This study is testing if using sleep studies can help people with motor neurone disease get better breathing support from non-invasive ventilation to improve their quality of life.
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Testing drugs to slow down motor neurone disease progression
This study is testing if the drug amantadine can help slow down motor neurone disease and improve survival for people living with it.
Related topics
Quick answers
How many Motor Neuron Disease, Amyotrophic Lateral Sclerosis clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (2 trials), United Kingdom (1 trial), Australia (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.