Condition

Monoclonal Gammopathy of Undetermined Significance (MGUS) clinical trials and research

• 6Clinical trials
• 8Countries

Newest Monoclonal Gammopathy of Undetermined Significance (MGUS) clinical trials

All recruiting trials (6)

• Multi-omics profiling to predict progression from MGUS and smoldering myeloma to symptomatic multiple myeloma

  This project will try to see if combined genomic, immune, and oral microbiome tests can predict which people with MGUS or smoldering myeloma will progress to symptomatic multiple myeloma.

  Recruiting Azienda USL Reggio Emilia - IRCCS · Bologna and 3 other locations · NCT07214324

• Analyzing gut microbiota in patients with monoclonal gammopathy

  This study is trying to see how the gut bacteria of people with monoclonal gammopathy differ from those without the condition to help find new ways to diagnose and treat it.

  Recruiting Zhujiang Hospital · Guanzhou, Guangdong · NCT06690593

• Identifying precancerous multiple myeloma in African American adults

  This study is testing a way to find early signs of multiple myeloma in Black and African American adults aged 30 and older to help catch it sooner and improve their health outcomes.

  Recruiting Wake Forest University Health Sciences · Charlotte, North Carolina · NCT06644625

• Testing linvoseltamab for eliminating abnormal plasma cells in patients with high-risk MGUS or smoldering multiple myeloma

  This study is testing if a new drug called linvoseltamab can help get rid of abnormal plasma cells in patients with high-risk MGUS or smoldering multiple myeloma.

  Recruiting at 39 sites Phase 2 Regeneron Pharmaceuticals · Baltimore, Maryland and 38 other locations · NCT06140524

• Cohort of patients with plasma cell disorders at Peking University First Hospital

  This study is looking at hospitalized patients with plasma cell disorders to see how their treatment and disease status affect their outcomes over time.

  Recruiting Peking University First Hospital · Beijing · NCT05283993

• Assessing molecular changes in blood cancers

  This study is trying to see how changes in blood samples from people with early blood cancers can help us understand their condition better and find new treatment options.

  Recruiting at 7 sites Dana-Farber Cancer Institute · Boston, Massachusetts and 6 other locations · NCT02269592

Related topics

Quick answers

How many Monoclonal Gammopathy of Undetermined Significance (MGUS) clinical trials are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (3 trials), Italy (2 trials), China (2 trials), Belgium (1 trial), France (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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