Condition

Mitral Valve Regurgitation clinical trials and research

• 10Clinical trials
• 14Countries

Newest Mitral Valve Regurgitation clinical trials

All recruiting trials (10)

• How TAVI and M‑TEER affect sleep‑disordered breathing

  This will see if adults with aortic stenosis or mitral regurgitation who undergo TAVI or M‑TEER have improvements in sleep‑disordered breathing six months after their procedure.

  Recruiting Hippocration General Hospital · Athens, Attica · NCT07520656

• Mitral and Tricuspid Valve-in-Valve/Valve-in-Ring Registry in Asia-Pacific

  This registry tracks people in Asia-Pacific who have had or will have valve-in-valve or valve-in-ring procedures for mitral or tricuspid valve disease to learn about outcomes and safety after these transcatheter approaches.

  Recruiting Prince of Wales Hospital, Shatin, Hong Kong · Hong Kong, Shatin · NCT07296016

• Evaluating heart recovery after surgery for aortic regurgitation

  This study looks at how heart surgery for aortic regurgitation helps people with heart problems feel better and recover by checking their heart function and quality of life afterward.

  Recruiting at 2 sites Petrovsky National Research Centre of Surgery · Moscow and 1 other locations · NCT06805253

• Evaluation of the AltaValve System for treating mitral regurgitation

  This study is testing a new device called the AltaValve System to see if it can help people with mitral regurgitation who can't have surgery feel better and improve their heart function.

  Recruiting at 58 sites 4C Medical Technologies, Inc. · Phoenix, Arizona and 57 other locations · NCT06465745

• Registry for MitraClip treatment of severe mitral valve regurgitation

  This study is testing how well the MitraClip G4 device works and is safe for people with severe mitral valve leakage who are getting a specific type of heart repair.

  Recruiting Fondazione GISE Onlus · San Donato Milanese, Milano · NCT05455489

• New treatment for severe mitral valve insufficiency using a transcatheter valve system

  This study is testing a new, less invasive heart valve replacement for older adults with severe mitral valve problems who can't have regular surgery.

  Recruiting at 8 sites Affluent Medical · Innsbruck and 9 other locations · NCT04775108

• Registry for patients undergoing transcatheter mitral or tricuspid valve therapy

  This study collects information from patients who have had transcatheter mitral or tricuspid valve therapy to see how well these treatments work over time.

  Recruiting Deutsches Herzzentrum Muenchen · Munich, Bavaria · NCT04577248

• Evaluation of a new transcatheter mitral valve replacement device

  This study is testing a new heart valve replacement device to see if it can safely help people with severe mitral valve problems who can't have regular surgery.

  Recruiting at 3 sites Shanghai NewMed Medical Co., Ltd. · Beijing, Beijing Municipality and 2 other locations · NCT04195984

• Replacement of the mitral valve using a new device for patients with severe mitral regurgitation

  This study is testing a new device to replace the mitral valve in patients with severe mitral regurgitation who can't use other treatments to see if it is safe and effective.

  Recruiting at 74 sites Medtronic Cardiovascular · Birmingham, Alabama and 84 other locations · NCT03242642

• Registry for tracking outcomes of mitral valve repair procedures

  This study is tracking the results of mitral valve repair procedures to see how well they work and improve care for patients undergoing this treatment.

  Recruiting American College of Cardiology · Washington D.C., District of Columbia · NCT02245763

Related topics

Quick answers

How many Mitral Valve Regurgitation clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in United States (3 trials), Greece (2 trials), Canada (2 trials), Germany (2 trials), Italy (2 trials). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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