Mitral and Tricuspid Valve-in-Valve/Valve-in-Ring Registry in Asia-Pacific
Official title: The Asia-Pacific Mitral & Tricuspid Valve-in-Valve/Valve-in-Ring Registry
Run by Prince of Wales Hospital, Shatin, Hong Kong · NCT07296016 · Data updated 2026-11-12
This registry tracks people in Asia-Pacific who have had or will have valve-in-valve or valve-in-ring procedures for mitral or tricuspid valve disease to learn about outcomes and safety after these transcatheter approaches.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 21 Years and up |
| Sex | All |
| Enrollment | 15 (estimated) |
| Sponsor | Prince of Wales Hospital, Shatin, Hong Kong Academic / other |
| Locations | 1 site (Hong Kong, Shatin) |
| Status | Recruiting |
| Started | June 29, 2026 |
| Main results expected | December 31, 2035 |
| Study ends | December 31, 2035 |
| Registry record updated | September 18, 2026 |
| Trial ID | NCT07296016 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 21 and older who have had or are planned to have a mitral or tricuspid valve-in-valve/valve-in-ring procedure, with no active endocarditis and no other disqualifying conditions as judged by investigators.
✕Probably not a fit
Patients with active infection, other major contraindications, or conditions deemed unsuitable by investigators may not benefit from or be relevant to the registry findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational registry collects data on adults 21 and older who have undergone or are planned to undergo mitral or tricuspid valve-in-valve or valve-in-ring procedures. It aims to describe real-world outcomes in the Asia-Pacific region, addressing gaps in long-term data and regional patient characteristics. The study includes retrospective cases from 2023 onward and prospective cases as they occur, focusing on safety, device performance, and clinical outcomes. Participating centers include Prince of Wales Hospital in Hong Kong and the National Heart Centre Singapore. The project seeks to inform clinicians on feasibility and potential benefits of transcatheter reinterventions in this regional population.
Why it matters
Potential benefit: If successful, the registry could clarify long-term safety and effectiveness of valve-in-valve/ring procedures in Asia-Pacific and guide clinical decision-making.
How similar studies have gone: Prior regional data on these procedures are limited; Western cohorts exist but long-term Asia-Pacific data are sparse, making this registry relatively novel for the region.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age ≥ 21 2. Had at least one documented Mitral valve-in-valve/valve-in-ring procedure done during the period of 1 Jan 2023 to current date. (Retrospective) OR Planned to undergo a Mitral valve-in-valve/valve-in-ring procedure. (Prospective) OR Had at least one documented Tricuspid valve-in-valve/valve-in-ring procedure done during the period of 1 Jan 2023 to current date. (Retrospective) OR Planned to undergo a Tricuspid valve-in-valve/valve-in-ring procedure. (Prospective) Exclusion Criteria: 1. Active endocarditis 2. Any other conditions which investigator deems unsuitable for participation.
Where it's running
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Prince of Wales Hospital
Hong Kong, Shatin, Hong Kong Recruiting
Study contacts
- Study coordinator: Chak Yu Kent So
- Email: scy309@ha.org.hk
- Phone: 852-35051518
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.