Registry for tracking outcomes of mitral valve repair procedures

The Society of Thoracic Surgeons/ American College of Cardiology Transcatheter Valve Therapies Registry Mitral Module

Observational American College of Cardiology · NCT02245763

This study is tracking the results of mitral valve repair procedures to see how well they work and improve care for patients undergoing this treatment.

Quick facts

Study typeObservational
Enrollment4000 (estimated)
Ages1 Year and up
SexAll
SponsorAmerican College of Cardiology Academic / other
Locations1 site (Washington D.C., District of Columbia)
Trial IDNCT02245763 on ClinicalTrials.gov

What this trial studies

The TVT Registry is a national surveillance system designed to monitor patient safety and real-world outcomes associated with transcatheter mitral valve repair (TMVR) procedures. It collects standardized data from participating hospitals to assess the quality of care for patients undergoing this treatment. The registry aims to provide confidential reports to healthcare providers to improve care quality and support research based on the collected data. Additionally, it serves as a scalable infrastructure for post-market studies of transcatheter valve therapies.

Who should consider this trial

Good fit: Ideal candidates for this registry include all patients undergoing transcatheter mitral valve repair procedures.

Not a fit: Patients who cannot tolerate anticoagulation or have active endocarditis or rheumatic mitral valve disease may not benefit from this registry.

Why it matters

Potential benefit: If successful, this registry could enhance the safety and effectiveness of mitral valve repair procedures, ultimately improving patient outcomes.

How similar studies have performed: Other national registries for transcatheter valve therapies have shown success in improving patient outcomes and safety monitoring.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients

Exclusion Criteria:

* Patients who cannot tolerate procedural anticoagulation or post procedural anti-platelet regimen
* Active endocarditis of the mitral valve
* Rheumatic mitral valve disease
* Evidence of intracardiac, inferior vena cava (IVC) or femoral venous thrombus

Where this trial is running

Washington D.C., District of Columbia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Mitral Valve Regurgitation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.