Condition

Metastatic Solid Tumors clinical trials and research

• 17Clinical trials
• 20Countries

Newest Metastatic Solid Tumors clinical trials

All recruiting trials (17)

• SLR-108 PET Imaging for Metastatic Solid Tumors

  A Phase 1 study to see if SLR-108 can be safely used for PET imaging of metastatic solid tumors in adults.

  Recruiting Phase 1 Solve Therapeutics · Newport Beach, California · NCT07728942

• TROP2-targeted CAR-NK cell therapy for advanced solid tumors

  This study tests EB-NK-301, an off-the-shelf CAR-NK cell therapy, in adults with advanced or metastatic TROP2-expressing solid tumors after standard treatments have failed.

  Recruiting Phase 1/2 Beijing Biotech · Shenzhen, Guangdong · NCT07589530

• Combining RAS(ON) inhibitors with ivonescimab for adults with RAS‑mutant advanced solid tumors

  This trial will test whether combining RAS(ON) inhibitors with ivonescimab is safe and can shrink or control tumors in adults with advanced or metastatic solid tumors that have RAS mutations.

  Recruiting at 19 sites Phase 1/2 Revolution Medicines, Inc. · Scottsdale, Arizona and 18 other locations · NCT07397338

• ADCX-020 treatment for advanced or metastatic solid tumors

  This trial will test ADCX-020, an antibody–drug conjugate, in adults with advanced or metastatic solid tumors who have run out of standard treatment options.

  Recruiting at 9 sites Phase 1 Adcytherix SAS · Sydney, New South Wales and 8 other locations · NCT07238075

• Sarah Nanotechnology System treatment using magnetic hyperthermia for advanced metastatic solid tumors

  This trial will try a single IV dose of iron-oxide nanoparticles followed by a low-frequency magnetic field to heat tumors in people with stage 4 metastatic solid tumors who have exhausted standard treatments.

  Recruiting New Phase Ltd. · Rochester, Minnesota · NCT07224464

• CKD-512 alone and with pembrolizumab for advanced or metastatic solid tumors

  This study will try CKD-512 by itself and together with pembrolizumab in people with advanced or metastatic solid tumors who have exhausted standard treatments.

  Recruiting Phase 1 Chong Kun Dang Pharmaceutical · Seoul · NCT07215637

• AVZO-103 alone and with other treatments for advanced urothelial and other solid tumors

  This trial will test intravenous AVZO-103, alone and combined with other cancer drugs, to see if it is safe and helps adults with locally advanced or metastatic urothelial cancer or other solid tumors.

  Recruiting at 15 sites Phase 1/2 Avenzo Therapeutics, Inc. · San Francisco, California and 14 other locations · NCT07193511

• DS3610a for adults with advanced or metastatic solid tumors

  This trial will test whether DS3610a is safe and helps adults with advanced or metastatic solid tumors.

  Recruiting at 4 sites Phase 1 Daiichi Sankyo · Milwaukee, Wisconsin and 3 other locations · NCT07159126

• SLV-324 for adults with metastatic solid tumors

  This will try SLV-324 given by IV infusion to see if it's safe and can shrink or slow metastatic solid tumors in adults who have progressed after standard treatments.

  Recruiting at 7 sites Phase 1 Solve Therapeutics · Newport Beach, California and 6 other locations · NCT07108114

• SKB107 for advanced solid tumors that have spread to bone

  This trial will test SKB107 in adults whose solid tumors have metastasized to bone to see if the drug is safe, how it behaves in the body, and whether it shows signs of benefit.

  Recruiting Phase 1 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. · Shanghai · NCT07087197

• AVZO-1418 alone and with other treatments for advanced epithelial solid tumors

  This trial will test whether intravenous AVZO-1418, alone or with other cancer drugs, is safe and helps adults with locally advanced or metastatic epithelial solid tumors, including some lung cancers.

  Recruiting at 27 sites Phase 1/2 Avenzo Therapeutics, Inc. · Gilbert, Arizona and 26 other locations · NCT07038343

• ERAS-4001 for advanced or metastatic solid tumors with KRAS mutations.

  This trial will try the oral drug ERAS-4001, alone or with other cancer therapies, in adults with advanced or metastatic solid tumors that have specific KRAS mutations.

  Recruiting at 5 sites Phase 1 Erasca, Inc. · Nashville, Tennessee and 4 other locations · NCT07021898

• Testing ERAS-0015 in patients with advanced solid tumors

  This study is testing a new drug called ERAS-0015 to see if it is safe and effective for people with advanced solid tumors that have certain RAS mutations.

  Recruiting at 13 sites Phase 1 Erasca, Inc. · Santa Rosa, California and 12 other locations · NCT06983743

• Evaluating ODC-IL2 for advanced or metastatic solid tumors

  This study is testing a new treatment called ODC-IL2 to see if it is safe and can help adults with advanced or metastatic solid tumors.

  Recruiting Phase 1 Trutino Biosciences Inc. · Scottsdale, Arizona · NCT06770764

• Evaluating the safety of INCA33890 for advanced or metastatic solid tumors

  This study is testing a new drug called INCA33890 to see if it's safe for people with advanced solid tumors who haven't had success with other treatments.

  Recruiting at 36 sites Phase 1 Incyte Corporation · Los Angeles, California and 38 other locations · NCT05836324

• Treatment with repotrectinib for young patients with specific genetic alterations in tumors

  This study is testing a new oral medication called repotrectinib to see if it can help young patients with advanced tumors that have certain genetic changes when other treatments haven't worked.

  Recruiting at 44 sites Phase 1/2 Turning Point Therapeutics, Inc. · Los Angeles, California and 67 other locations · NCT04094610

• Testing repotrectinib in patients with advanced solid tumors with specific gene rearrangements

  This study is testing a new drug called repotrectinib to see if it can help people with advanced solid tumors that have certain gene changes.

  Recruiting at 63 sites Phase 1/2 Turning Point Therapeutics, Inc. · Duarte, California and 164 other locations · NCT03093116

Related topics

Quick answers

How many Metastatic Solid Tumors clinical trials are recruiting right now?

17, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 20 countries. The most sites are in United States (13 trials), China (5 trials), France (4 trials), South Korea (4 trials), Spain (4 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 10, Phase 1/2: 6. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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