Condition
Malignant Peripheral Nerve Sheath Tumor (MPNST) clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Malignant Peripheral Nerve Sheath Tumor (MPNST) clinical trials that are recruiting, at sites in 2 countries (most in United States (2), China (1)). By phase: Phase 1/2 (2), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 2Countries
Newest Malignant Peripheral Nerve Sheath Tumor (MPNST) clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Combining immune therapy with chemotherapy for advanced soft tissue sarcoma | Phase 2 | Shanghai, Shanghai Municipality | Recruiting | Feb 27, 2025 |
| MeK and MDM2 inhibitors in NF1-related tumors | Phase 1/2 | Washington D.C., District of Columbia and 1 other locations | Recruiting | Dec 16, 2024 |
| Investigating afamitresgene autoleucel for pediatric cancers | Phase 1/2 | Palo Alto, California and 9 other locations | Recruiting | Dec 8, 2022 |
All recruiting trials (3)
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Combining immune therapy with chemotherapy for advanced soft tissue sarcoma
This study is testing if combining a new immune therapy with standard chemotherapy can help people with advanced soft tissue sarcoma who can’t have surgery or radiation feel better and live longer.
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MeK and MDM2 inhibitors in NF1-related tumors
This study tests a combination of selumetinib and APG-115 in adults and older teens with NF1 who have unresectable or metastatic MPNST or related conditions to see if the treatment is tolerable and helps slow or stop tumor growth.
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Investigating afamitresgene autoleucel for pediatric cancers
This study is testing a new treatment called afamitresgene autoleucel to see if it can help children and young adults with certain advanced cancers that have specific genetic markers.
Related topics
Quick answers
How many Malignant Peripheral Nerve Sheath Tumor (MPNST) clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (2 trials), China (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1/2: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.