Condition
Locally Advanced Gastroesophageal Junction Adenocarcinoma clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Locally Advanced Gastroesophageal Junction Adenocarcinoma clinical trials that are recruiting, at sites in 2 countries (most in United States (4), China (1)). By phase: Phase 1 (2), Phase 2 (2), Phase 1/2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 2Countries
Newest Locally Advanced Gastroesophageal Junction Adenocarcinoma clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Combining two anticancer drugs for treating advanced gastric and gastroesophageal junction cancers | Phase 1 | Houston, Texas | Recruiting | Apr 15, 2024 |
| Using propranolol with pembrolizumab and chemotherapy for advanced esophageal cancer | Phase 2 | Buffalo, New York | Recruiting | Dec 15, 2022 |
| Personalized vaccine combined with pembrolizumab for advanced solid tumors | Phase 1/2 | Jacksonville, Florida | Recruiting | Mar 8, 2022 |
| Combination of chemotherapy and immunotherapy for advanced esophagogastric junction cancer | Phase 2 | Guangzhou, Guangdong | Recruiting | Aug 4, 2021 |
| Combining trifluridine/tipiracil with talazoparib for advanced colorectal or gastroesophageal cancer | Phase 1 | Buffalo, New York | Recruiting | Aug 12, 2020 |
All recruiting trials (5)
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Combining two anticancer drugs for treating advanced gastric and gastroesophageal junction cancers
This study is testing a new combination of two cancer drugs to see if they can help people with advanced HER2-positive gastric or gastroesophageal junction cancers feel better and live longer.
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Using propranolol with pembrolizumab and chemotherapy for advanced esophageal cancer
This study is testing whether adding propranolol to the cancer drug pembrolizumab and standard chemotherapy can help people with advanced esophageal cancer live longer and feel better.
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Personalized vaccine combined with pembrolizumab for advanced solid tumors
This study is testing a new personalized cancer vaccine combined with pembrolizumab to see if it helps people with advanced solid tumors fight their cancer better.
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Combination of chemotherapy and immunotherapy for advanced esophagogastric junction cancer
This study is testing if combining a new immune therapy with chemotherapy can help people with advanced esophagogastric junction cancer have smaller tumors that are easier to remove and improve their chances of living longer.
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Combining trifluridine/tipiracil with talazoparib for advanced colorectal or gastroesophageal cancer
This study is testing a new combination of two cancer drugs to see if they can safely help people with advanced colorectal or gastroesophageal cancer.
Related topics
Quick answers
How many Locally Advanced Gastroesophageal Junction Adenocarcinoma clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (4 trials), China (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 2, Phase 2: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.