Condition

Metastatic Gastroesophageal Junction Adenocarcinoma clinical trials and research

• 10Clinical trials
• 3Countries

Newest Metastatic Gastroesophageal Junction Adenocarcinoma clinical trials

All recruiting trials (10)

• Combining two anticancer drugs for treating advanced gastric and gastroesophageal junction cancers

  This study is testing a new combination of two cancer drugs to see if they can help people with advanced HER2-positive gastric or gastroesophageal junction cancers feel better and live longer.

  Recruiting Phase 1 National Cancer Institute (NCI) · Houston, Texas · NCT06364410

• Combination treatment for advanced gastric cancer

  This study is testing a new combination of treatments for people with advanced stomach cancer to see if it can help improve their health and fight the disease better.

  Recruiting Phase 1/2 Henan Cancer Hospital · Zhengzhou, Henan · NCT06329973

• Combining Nivolumab with Standard Treatment for Advanced Stomach or Esophageal Cancer

  This study is testing if adding nivolumab to the usual treatments for advanced stomach or esophageal cancer can help patients live longer and feel better.

  Recruiting at 338 sites Phase 2/3 National Cancer Institute (NCI) · Little Rock, Arkansas and 377 other locations · NCT06203600

• CPI-613 combined with hydroxychloroquine and chemotherapy for advanced solid tumors

  This study is testing a new combination of treatments, including CPI-613 and hydroxychloroquine, to see if it can help people with advanced solid tumors that haven't improved with other chemotherapy.

  Recruiting Phase 2 Northwestern University · Chicago, Illinois · NCT05733000

• Comparing two chemotherapy regimens for advanced HER2 negative gastric and esophageal cancer

  This study is testing if a new chemotherapy combination can help people with advanced HER2 negative stomach and esophageal cancer live longer compared to the standard treatment.

  Recruiting at 626 sites Phase 3 Alliance for Clinical Trials in Oncology · Birmingham, Alabama and 801 other locations · NCT05677490

• Using propranolol with pembrolizumab and chemotherapy for advanced esophageal cancer

  This study is testing whether adding propranolol to the cancer drug pembrolizumab and standard chemotherapy can help people with advanced esophageal cancer live longer and feel better.

  Recruiting Phase 2 Roswell Park Cancer Institute · Buffalo, New York · NCT05651594

• Personalized vaccine combined with pembrolizumab for advanced solid tumors

  This study is testing a new personalized cancer vaccine combined with pembrolizumab to see if it helps people with advanced solid tumors fight their cancer better.

  Recruiting Phase 1/2 Mayo Clinic · Jacksonville, Florida · NCT05269381

• Combination therapy for gastric cancer with inoperable bowel obstruction

  This study is testing a combination of three cancer drugs to see if it can help people with gastric cancer and a blocked bowel feel better and improve their condition.

  Recruiting Phase 2 Sixth Affiliated Hospital, Sun Yat-sen University · Guangzhou, Guangdong · NCT04840264

• Combining trifluridine/tipiracil with talazoparib for advanced colorectal or gastroesophageal cancer

  This study is testing a new combination of two cancer drugs to see if they can safely help people with advanced colorectal or gastroesophageal cancer.

  Recruiting Phase 1 Roswell Park Cancer Institute · Buffalo, New York · NCT04511039

• Using radiation therapy to treat metastatic gastrointestinal cancers

  This study tests if adding radiation therapy to immunotherapy can help people with metastatic gastrointestinal cancers feel better and improve their disease status.

  Recruiting University of California, San Francisco · San Francisco, California and 1 other locations · NCT04221893

Related topics

Quick answers

How many Metastatic Gastroesophageal Junction Adenocarcinoma clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in United States (8 trials), China (2 trials), Puerto Rico (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 1/2: 2, Phase 1: 2, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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