Condition

Locally Advanced Cervical Cancer clinical trials and research

• 17Clinical trials
• 2NIH research projects
• 1New in 30 days
• 21Countries

Newest Locally Advanced Cervical Cancer clinical trials

All recruiting trials (17)

• Iparomlimab/Tuvonralimab with nab-paclitaxel and cisplatin as neoadjuvant therapy for locally advanced cervical cancer

  This trial tests whether adding Iparomlimab/Tuvonralimab to nab-paclitaxel and cisplatin before surgery can shrink locally advanced cervical cancer and safely be given to adult women.

  Recruiting Phase 2 Xijing Hospital · Xi'an, Shaanxi · NCT07876154

• Vitamin D Status and Outcomes in Locally Advanced Cervical Cancer treated with chemoradiotherapy

  This study tests whether pretreatment vitamin D levels can predict how well women with locally advanced cervical cancer respond to standard chemoradiotherapy.

  Recruiting University of Kragujevac · Kragujevac, Šumadija · NCT07743918

• Patient-tailored 3D-printed ARCHITECT applicator for cervical cancer brachytherapy

  We’re testing a 3D-printed, one-time use ARCHITECT applicator to see if it safely helps deliver brachytherapy for locally advanced cervical cancer.

  Recruiting Erasmus Medical Center · Rotterdam · NCT07435987

• Nanocrystalline megestrol acetate with chemoradiation for locally advanced cervical cancer

  This Phase 1 trial tests whether taking nanocrystalline megestrol acetate by mouth can prevent or reduce weight and muscle loss in adults with locally advanced cervical cancer who are receiving concurrent chemoradiotherapy.

  Recruiting Phase 1 Second Xiangya Hospital of Central South University · Changsha, Hunan · NCT07338487

• Cadonilimab plus cisplatin given before surgery for locally advanced cervical cancer

  This study will test whether giving cadonilimab together with cisplatin before surgery helps people with resectable, locally advanced cervical cancer.

  Recruiting Phase 2 The First Affiliated Hospital of Zhengzhou University · Zhengzhou, Henan · NCT07104149

• Pre-surgery iparomlimab and tuvonralimab with chemotherapy for locally advanced cervical cancer

  This phase 2 trial tests whether giving iparomlimab and tuvonralimab with chemotherapy before surgery helps people with locally advanced cervical cancer shrink their tumors and improve outcomes.

  Recruiting Phase 2 Fujian Cancer Hospital · Fuzhou, Fujian · NCT07055399

• Understanding cervical cancer treatment and characteristics in Italy

  This study looks at how patients in Italy with advanced or recurring cervical cancer are treated and what their experiences are like.

  Recruiting at 10 sites MSD Italia S.r.l. · Bologna, Bologna and 10 other locations · NCT06771193

• Comparing neoadjuvant chemoimmunotherapy and concurrent chemoradiotherapy for locally advanced cervical cancer

  This study is testing whether a new treatment combining chemoimmunotherapy and surgery can help people with locally advanced cervical cancer do better than the standard treatment of chemo and radiation.

  Recruiting at 12 sites Phase 2/3 Tongji Hospital · Hefei, Anhui and 11 other locations · NCT06288373

• Neoadjuvant immunochemotherapy for PD-L1-negative locally advanced cervical cancer

  This study is testing a new treatment that combines chemotherapy with a drug called Camrelizumab to see if it can help people with PD-L1-negative locally advanced cervical cancer before surgery.

  Recruiting at 12 sites Phase 2 Tongji Hospital · Hefei, Anhui and 11 other locations · NCT06288360

• Comparing Cisplatin and Gemcitabine with Radiotherapy for Cervical Cancer

  This study is testing whether using Cisplatin or Gemcitabine along with radiation can help people with locally advanced cervical cancer feel better and improve their outcomes.

  Recruiting Phase 3 National Institute of Cancerología · Mexico City, Mexico City · NCT06156514

• Curcumin supplementation for patients with locally advanced cervical cancer

  This study is testing if adding curcumin to the treatment of patients with locally advanced cervical cancer can improve their outcomes and find the safest dose to use.

  Recruiting National Institute of Cancerología · Mexico City, Mexico City · NCT06080841

• Treatment for women with high-risk locally advanced cervical cancer

  This study is testing if a new treatment called volrustomig can help women with high-risk locally advanced cervical cancer feel better after their initial treatment.

  Recruiting at 145 sites Phase 3 AstraZeneca · Birmingham, Alabama and 204 other locations · NCT06079671

• Combining Zimberelimab with Paclitaxel and Cisplatin for Cervical Cancer Treatment

  This study is testing if a new treatment combining Zimberelimab with two chemotherapy drugs can help women with advanced cervical cancer shrink their tumors before surgery.

  Recruiting Phase 2 Tang-Du Hospital · Xi'an, Shaanxi · NCT06055738

• Assessing the effects of radiotherapy on tumors in cervical and pancreatic cancer

  This study is testing how radiotherapy affects tumors in patients with locally advanced cervical and pancreatic cancer by collecting samples and using special imaging before, during, and after treatment.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT05975593

• Examining the link between plasma MRD and HPV DNA in advanced cervical cancer treatment outcomes

  This study is testing if measuring certain markers in the blood can help predict how well treatment works for people with advanced cervical cancer.

  Recruiting Guizhou Provincial People's Hospital · Guiyang, Guizhou · NCT05950087

• Combining Cadonilimab with Radiotherapy for Advanced Cervical Cancer

  This study is testing if a new treatment combining Cadonilimab with radiation therapy can help women with advanced cervical cancer who can't handle chemotherapy.

  Recruiting Phase 2 Chongqing University Cancer Hospital · Chongqing, CHN · NCT05687851

• Comparing surgery and imaging methods for staging cervical cancer

  This study is testing whether using surgery or imaging methods to stage cervical cancer helps patients live longer and feel better.

  Recruiting Chongqing University Cancer Hospital · Chongqing, Chongqing Municipality · NCT05378087

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Globally useful predictor for cervical cancer treatment response

  This project aims to develop a simple predictive signature to personalize treatment for locally advanced cervical cancer using easy tests and imaging.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11622628

• Understanding how immunotherapy and radiation work together for cervical cancer

  This project aims to find better ways to predict which patients with advanced cervical cancer will respond best to a combination of immunotherapy and chemotherapy with radiation.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11133049

Related topics

Quick answers

How many Locally Advanced Cervical Cancer clinical trials are recruiting right now?

17, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 21 countries. The most sites are in China (11 trials), Mexico (3 trials), United States (2 trials), Italy (2 trials), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Phase 3: 2, Phase 1: 1, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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