Clinical trial Recruiting at 10 sites Observational Ages 18 and up Women only

Understanding cervical cancer treatment and characteristics in Italy

Official title: RETRACE Study - Retrospective Observational Study Evaluating Disease Characteristics and Treatment Landscape of High-risk Locally Advanced (LA) or Recurrent / Metastatic (R/M) Cervical Cancer in Italy

Run by MSD Italia S.r.l. · NCT06771193 · Data updated 2026-11-12

This study looks at how patients in Italy with advanced or recurring cervical cancer are treated and what their experiences are like.

More Cervical Cancer trials

Quick facts

Study typeObservational
Ages18 Years and up
SexWomen only
Enrollment200 (estimated)
SponsorMSD Italia S.r.l.
Industry-sponsored
Drugs / interventionsPembrolizumab, Levantinib
Locations11 sites (Bologna, Bologna and 10 other locations)
StatusRecruiting
StartedDecember 17, 2024
Main results expectedDecember 2025
Study endsDecember 2025
Registry record updatedJuly 20, 2025
Trial IDNCT06771193 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older diagnosed with locally advanced, recurrent, or metastatic cervical cancer who received treatment between January 2018 and December 2021.

Probably not a fit

Patients currently participating in pharmacological clinical trials or those treated with specific medications like Pembrolizumab, Olaparib, or Levantinib may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to analyze the characteristics and treatment patterns of patients with locally advanced or recurrent/metastatic cervical cancer in Italy. By reviewing medical records from oncologic clinics between January 2018 and December 2021, the study will capture data on patient demographics, disease characteristics, and treatment approaches. The study will categorize patients based on risk levels and assess differences in treatment strategies. This retrospective analysis will provide valuable insights into the management of cervical cancer in the specified population.

Why it matters

Potential benefit: If successful, this study could enhance understanding of cervical cancer treatment patterns, potentially leading to improved patient outcomes.

How similar studies have gone: While this study is observational and retrospective, similar studies have provided valuable insights into treatment patterns and outcomes in cancer care.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient (or their legally acceptable representatives) must have signed and dated the Informed Consent \& Privacy Form (ICF)
* Age ≥18 years
* Diagnosis of a cervical cancer
* Locally advanced stage (not suitable for curative surgery) or recurrent or metastatic disease
* Any treatment received between January 2018 and December 2021 for advanced disease

Exclusion Criteria:

* Patients participating in a pharmacological clinical trial for the treatment of advanced disease
* Patients who participated in a clinical trial
* Patients who were administered with Pembrolizumab, Olaparib or Levantinib or medications from these class of drugs

Where it's running

  • Oncologia Medica Policlinico Sant'Orsola Malpighi
    Bologna, Bologna, Italy
    Recruiting
  • Ginecologia ed Ostetricia A.O. Cannizzaro
    Catania, Catania, Italy
    Recruiting
  • Oncologia Medica 1 IRCCS Ospedale Policlinico San Martino
    Genova, Genova, Italy
    Recruiting
  • Unità di Ginecologia Oncologica Medica IRCCS Ospedale San Raffaele
    Milan, Milano, Italy
    Recruiting
  • Unità Ostetricia, Ginecologia e Ginecologia Oncologica medica Humanitas San Pio X
    Milan, Milano, Italy
    Recruiting
  • Oncologia A.O.U. di Modena - Policlinico
    Modena, Modena, Italy
    Recruiting
Show 5 more locations
  • U.O.S. Trattamenti Innovativi dell'utero Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale
    Naples, Napoli, Italy
    Recruiting
  • UOC Oncologia Medica ed Ematologia Azienda Ospedaliera Universitaria Luigi Vanvitelli
    Naples, Napoli, Italy
    Recruiting
  • IRCCS Centro di Riferimento Oncologico (CRO)
    Aviano, Pordenone, Italy
    Recruiting
  • U.O.C. Ginecologia Oncologica Policlinico Agostino Gemelli
    Roma, Roma, Italy
    Recruiting
  • UOC Oncologia Medica Ospedale Dell'Angelo - Mestre Azienda USL3 Serenissima
    Mestre, Venezia, Italy
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.