Condition

IDH Mutation clinical trials and research

• 5Clinical trials
• 4Countries

Newest IDH Mutation clinical trials

All recruiting trials (5)

• Patient experiences during treatment for IDH‑mutant grade 2 gliomas: vorasidenib, radiotherapy, or observation

  This project will test how adults with IDH‑mutant grade 2 gliomas feel—their quality of life, treatment symptoms, and anxiety—when they receive vorasidenib, radiotherapy, or active surveillance.

  Recruiting Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta · Milan · NCT07547163

• Ivosidenib as maintenance after adjuvant chemotherapy for curative IDH1‑mutant intrahepatic cholangiocarcinoma

  This trial tests whether taking ivosidenib after standard adjuvant chemotherapy can reduce recurrence in adults with completely removed (R0) IDH1‑mutant intrahepatic cholangiocarcinoma.

  Recruiting at 15 sites Phase 2 Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest · Aachen and 14 other locations · NCT07260175

• Testing DSP-0390 in patients with IDH-mutant gliomas

  This study is testing a new drug called DSP-0390 in patients with specific types of brain tumors to see if it helps kill more tumor cells during surgery.

  Recruiting Early Phase 1 Washington University School of Medicine · St Louis, Missouri · NCT06636162

• Combining All-Trans Retinoic Acid and PD-1 Inhibition for Recurrent IDH-Mutant Glioma

  This study is testing if a combination of a vitamin A derivative and a cancer immunotherapy can help people with recurrent IDH-mutant glioma feel better and fight their tumors.

  Recruiting Phase 2 Abramson Cancer Center at Penn Medicine · Philadelphia, Pennsylvania · NCT05345002

• Metabolic analysis of brain tumors using advanced MRI techniques

  This study is testing advanced MRI techniques to see if they can help identify specific changes in brain tumors that could improve treatment and survival for patients with gliomas.

  Recruiting Insel Gruppe AG, University Hospital Bern · Bern · NCT04233788

Related topics

Quick answers

How many IDH Mutation clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in United States (2 trials), Germany (1 trial), Switzerland (1 trial), Italy (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →