Defining how much No.4sb lymph node to remove for advanced distal stomach cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study at Tianjin Medical University Cancer Hospital follows adults with clinically T2-4a distal gastric cancer who undergo radical laparoscopic distal subtotal gastrectomy (D2, R0). Surgeons will record the precise anatomical extent of No.4sb lymph node dissection, operative details, and perioperative complications. Pathology will report nodal involvement and yield, and investigators will correlate dissection range with patterns of metastasis, surgical morbidity, and early oncologic outcomes. The goal is to identify a reasonable dissection boundary that balances thorough cancer removal with operative safety.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 and ≤ 75 years of age; Preoperative gastric cancer patients with pathologically confirmed; Had been treated with Radical resection (D2, R0) of gastric cancer (Lymph node≥16); Willing and able to comply with the program during the study period; Physical condition and organ function allows to tolerable abdominal surgery; Written informed consent provided; Under radical laparoscopic distal subtotal gastrectomy With more than a 6-month life expectancy; No other serious concomitant diseases; Sufficient organ functions; No previous history of chemotherapy or radiotherapy; Clinical stage: T2-4aNxM0; Karnofsky performance status (KPS)\>60; Eastern Cooperative Oncology Group Performance Status (ECOG): 0-1.

Exclusion Criteria:

Pregnancy or breast feeding; Patients with Serious liver disease (such as cirrhosis, etc.), kidney disease, respiratory disease or uncontrolled diabetes, hypertension and other chronic systemic diseases, heart disease with Clinical symptoms, such as congestive heart failure, coronary heart disease symptoms, drug is difficult to control arrhythmia, hypertension, or six months had a myocardial infarction attack, or cardiac insufficiency; Organ transplantation patients need immunosuppressive therapy; Severe recurrent infections were not controlled or with other serious concomitant diseases; Patients got other primary malignant tumors (except curable skin basal cell carcinoma and cervical cancer in situ) except gastric cancer within 5 years; Psychiatric disease which require treatment; Have the history of organ transplantation; Within 6 months before study starts and in the process of this study, patients participate in other clinical researches.

Where it's running

• Tianjin Medical University Cancer Hospital
  Tianjin, Tianjin Municipality, China Recruiting

Study contacts

• Study coordinator: Bin Ke, MD.
• Email: binke@tmu.edu.cn
• Phone: +86 022-23340123-1061

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.