Comparing two imaging techniques for gastrointestinal surgeries
Official title: Comparison Between Fluorescenceimaging With Photoplethysmography （PPG） and Indocyaningreen (ICG) for Tissue Perfusion in Gastrointestinal Resections
Run by Saint Petersburg State University, Russia · NCT06222645 · Data updated 2026-11-12
This study is testing two different imaging methods to see which one better helps doctors check blood flow in patients who have had gastrointestinal surgeries.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Saint Petersburg State University, Russia Academic / other |
| Locations | 3 sites (Yantai, Shandong and 2 other locations) |
| Status | Recruiting |
| Started | November 1, 2023 |
| Main results expected | April 30, 2026 |
| Study ends | May 31, 2026 |
| Registry record updated | November 18, 2025 |
| Trial ID | NCT06222645 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients undergoing gastrointestinal anastomoses who can provide informed consent.
✕Probably not a fit
Patients who are unable to consent or have an allergy to indocyanine green dye will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study examines gastrointestinal anastomoses using two imaging techniques: Imaging Photoplethysmography (iPPG) and Standard Routine Indocyanine Green (ICG) Imaging. The iPPG is a non-invasive method that detects blood pulsation in vessels using a conventional video camera, while ICG is a fluorescence imaging technique used to measure tissue perfusion. Both methods will be applied to patients with gastrointestinal anastomoses, and their perfusion data will be compared to evaluate the effectiveness of iPPG against the standard ICG method.
Why it matters
Potential benefit: If successful, this study could provide a more effective and non-invasive method for assessing tissue perfusion during gastrointestinal surgeries.
How similar studies have gone: While the use of ICG is well-established, the application of iPPG in this context is novel and has not been extensively tested in similar studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients (age ≥ 18 years). * Scheduled to undergo an elective gastrointestinal resection requiring a primary gastro-intestinal or entero-enteric anastomosis. * Able to understand and provide written informed consent. Exclusion Criteria: * Known hypersensitivity or allergy to indocyanine green (ICG), iodine, or any component of the ICG formulation. * Severe hepatic impairment (e.g., Child-Pugh Class C). * Pregnancy or lactation. * Emergency surgery. * Inability to comply with the study protocol or follow-up schedule in the investigator's judgment.
Where it's running
-
Shandong Linglong Yingcheng Hospital
Yantai, Shandong, China Recruiting -
Department of Faculty Surgery, Saint Petersburg State University
Saint Petersburg, Leningradskaya Oblast', Russia Recruiting -
High-Tech Clinic Beloostrov
Saint Petersburg, Leningradskaya Oblast', Russia Active not recruiting
Study contacts
- Study coordinator: Xuan - Qiu, MD
- Email: st122986@student.spbu.ru
- Phone: 79643411524
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.