Condition

Executive Dysfunction clinical trials and research

• 11Clinical trials
• 5NIH research projects
• 6Countries

Newest Executive Dysfunction clinical trials

All recruiting trials (11)

• Personalized E-Fit program to help executive skills in kids with complex congenital heart disease

  A tailored digital training program called E-Fit tests whether targeted brain-training, online coaching, and hands-on games can improve everyday executive skills in 9- to 13-year-olds who have complex congenital heart disease.

  Recruiting University Children's Hospital, Zurich · Zurich, Canton of Zurich · NCT07692958

• Intensive neurofeedback for children with ADHD: personalized vs. standard theta-beta training

  This study tests two neurofeedback approaches in children with ADHD to see if a personalized, iAPF-based theta-beta training works better than a standard theta-beta training.

  Recruiting at 2 sites Bielefeld University · Bielefeld and 1 other locations · NCT07595783

• Methylphenidate for attention and executive problems in children with sickle cell disease

  This study will test whether once-daily extended-release methylphenidate for 4 weeks helps attention and thinking skills in children 8–17 with sickle cell disease while monitoring side effects and adherence.

  Recruiting Phase 1 St. Jude Children's Research Hospital · Memphis, Tennessee · NCT07226219

• Transcranial direct current stimulation plus ABA to boost language and executive skills in children with autism.

  This project will test whether adding low-level electrical brain stimulation (tDCS) to applied behavior analysis helps children ages 5–12 with autism learn language and executive function skills better.

  Recruiting New York State Institute for Basic Research · Staten Island, New York · NCT07092280

• Exploring cognitive and emotional well-being in adolescents with idiopathic generalized epilepsy

  This study is trying to see how epilepsy affects the thinking and feelings of teenagers aged 11 to 18, along with their caregivers, to help improve their overall well-being.

  Recruiting IRCCS National Neurological Institute "C. Mondino" Foundation · Pavia · NCT06782074

• Understanding adolescent health and well-being in Singapore

  This study looks at how lifestyle, growth, and surroundings affect the health of 13 to 15-year-olds in Singapore to find ways to help them feel better and thrive.

  Recruiting Institute for Human Development and Potential (IHDP), Singapore · Singapore, Singapore and 1 other locations · NCT06622681

• Improving executive functioning in teens with epilepsy through a web-based intervention

  This study is testing a new online program to see if it can help teenagers with epilepsy improve their thinking skills and overall quality of life.

  Recruiting at 3 sites Children's Hospital Medical Center, Cincinnati · Orange, California and 2 other locations · NCT06608966

• Investigating the Role of Brain Signals in Working Memory

  This study is testing how different types of brain stimulation can improve working memory in people by looking at their brain activity during memory tasks.

  Recruiting Florida State University · Tallahassee, Florida · NCT06126809

• Exploring profiles in adults with binge eating disorder

  This study is trying to see if different emotional and thinking patterns in adults with binge eating disorder can help predict how well they respond to treatment over time.

  Recruiting at 2 sites Aarhus University Hospital · Aarhus, Central Jutland and 2 other locations · NCT05726721

• Non-invasive brain stimulation to improve cognitive and motor function in dementia patients

  This study is testing whether a new brain stimulation treatment at home can help improve memory and movement in older adults with mild cognitive impairment or mild dementia.

  Recruiting Hebrew SeniorLife · Boston, Massachusetts · NCT05661084

• Digital treatment for depression and cognitive issues after stroke

  This study is testing a digital program that uses an iPad and virtual coaching to help people who have had a stroke deal with depression and improve their thinking skills.

  Recruiting Phase 2 Weill Medical College of Cornell University · New York, New York · NCT05507138

NIH-funded research (5)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Could low brain iron affect thinking and self-control in kids and teens

  This work explores whether low iron in the brain is linked to attention, memory, and self-control problems in children and adolescents, including those with ADHD.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11163536

• Investigating how brain iron levels affect executive function in adolescents

  This study is looking at how not having enough iron in the brain might affect thinking skills, like remembering things and controlling impulses, in teenagers, including those with mental health challenges, to help find better ways to support them.

  NIH research University of Minnesota · Minneapolis, United States · NIH-10899628

• Improving mood and cognitive function after stroke using a digital intervention

  This study is testing a new online program to help improve mood and thinking skills for people who have had a stroke, making it easier for them to feel better and manage their daily lives.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-10873174

• Understanding executive dysfunction in adults with Down syndrome and its impact on work readiness.

  This study is looking at how challenges with planning and organization can impact job success for adults with Down syndrome, and it aims to gather information from caregivers to help improve their chances of finding and keeping a job.

  NIH research Drexel University · Philadelphia, United States · NIH-10531698

• Investigating how executive dysfunction affects adults with Down syndrome.

  This study is looking at how challenges with thinking and planning affect the daily lives of young adults with Down syndrome, and it hopes to find ways to help improve their job opportunities and everyday skills.

  NIH research Drexel University · Philadelphia, United States · NIH-10295990

Related topics

Quick answers

How many Executive Dysfunction clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (6 trials), Switzerland (1 trial), Singapore (1 trial), Italy (1 trial), Denmark (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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